Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LYN | P07948 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330590 | 0.76 | L3MBTL1 (0.49) | LMNAHTTCYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL10438124 | 0.70 | MAT2A (0.38) | SMN1; SMN2LYNALDH1A1KMT2AELANE | |
| SCHEMBL11882639 | 0.67 | LYN (0.67) | HTTLYNALDH1A1LTA4HTSHR | |
| SCHEMBL1513623 | 0.67 | ADORA2A (0.46) | HTTCYP1A2CYP2C19ALDH1A1KMT2A | |
| SCHEMBL6128622 | 0.67 | NPC1 (0.43) | CYP1A2CYP2C19SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL28328029 | 0.66 | LMNA (0.53) | LMNAHTTCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL4016272 | 0.65 | — | — | |
| SCHEMBL23123901 | 0.65 | KMT2A (0.41) | LMNAHTTBRD4CYP1A2CYP2C19 | |
| SCHEMBL29041274 | 0.64 | PIN1 (0.60) | LMNAHTTCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL20998690 | 0.64 | CRHBP (0.55) | LMNAHTTCYP1A2CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179875-A1 | SULFURIZATION REAGENTS ON SOLID SUPPORTS | GIRINDUS AMERICA, INC. (US) | 2014-06-26 | — | — | US | disclosed |
| WO-2013017469-A1 | SULFURIZATION REAGENTS ON SOLID SUPPORTS | GIRINDUS AMERICA, INC. (US) | 2013-02-07 | — | — | WO | disclosed |
| US-20120071640-A1 | Sulfurizing reagents and their use for oligonucleotides synthesis | GIRINDUS AMERICA, INC. (US) | 2012-03-22 | — | — | US | disclosed |
| EP-2382227-A1 | SULFURIZING REAGENTS AND THEIR USE FOR OLIGONUCLEOTIDES SYNTHESIS | Girindus America, Inc. (US) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010072831-A1 | SULFURIZING REAGENTS AND THEIR USE FOR OLIGONUCLEOTIDES SYNTHESIS | GIRINDUS AMERICA, INC (US) | 2010-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071640-A1 | Sulfurizing reagents and their use for oligonucleotides synthesis | RRM1, SRRT, NSUN2 | LMNA 2016/4885HTT 2793/4885BRD4 3845/4885 |
| US-20140179875-A1 | SULFURIZATION REAGENTS ON SOLID SUPPORTS | OR10J3, RPS8, NSUN2 | LMNA 3685/4885HTT 2609/4885BRD4 1162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.