Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 4/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | TOP1 | P11387 | 3/20 | 0.31 |
| ▸ | TOP2A | P11388 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15443267 | 0.74 | ABL1 (0.51) | DDR1 | |
| SCHEMBL15442436 | 0.72 | MAOA (0.43) | FLT3MAOAMAOBTOP1TOP2A | |
| SCHEMBL23048987 | 0.72 | FLT3 (0.34) | FLT3MAOAMAOBTOP1TOP2A | |
| SCHEMBL20144339 | 0.70 | HDAC6 (0.46) | SMN1; SMN2ALDH1A1MEN1KMT2ASLCO2B1 | |
| SCHEMBL15443081 | 0.67 | ABL1 (0.51) | DDR1 | |
| SCHEMBL20144337 | 0.67 | NPBWR1 (0.44) | FLT3MAOAMAOBSMN1; SMN2ALDH1A1 | |
| SCHEMBL15445593 | 0.65 | MAOA (0.41) | FLT3MAOAMAOBSMN1; SMN2ALDH1A1 | |
| SCHEMBL16283150 | 0.59 | NPC1 (0.44) | FLT3MAOAMAOBSMN1; SMN2ALDH1A1 | |
| SCHEMBL25343812 | 0.56 | MAOA (0.45) | MAOAMAOBALDH1A1 | |
| SCHEMBL20982767 | 0.55 | CBFB (0.69) | MAOAMAOBSMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3186247-B1 | PROTEIN KINASE INHIBITORS | ASTAR BIOTECH LLC (US) | 2021-03-03 | — | — | EP | disclosed |