Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15445593 | 0.90 | MAOA (0.41) | NPBWR1MAOAMAOBNPC1RAB9A | |
| SCHEMBL16283150 | 0.83 | NPC1 (0.44) | MAOAMAOBNPC1RAB9APKM | |
| SCHEMBL15442436 | 0.80 | MAOA (0.43) | NPBWR1MAOAMAOBNPC1RAB9A | |
| SCHEMBL15443081 | 0.75 | ABL1 (0.51) | — | |
| SCHEMBL23049050 | 0.74 | NPBWR1 (0.42) | NPBWR1NPC1RAB9APKMSMN1; SMN2 | |
| SCHEMBL12347958 | 0.69 | NPC1 (0.68) | NPBWR1NPC1RAB9APKMSMN1; SMN2 | |
| SCHEMBL29848567 | 0.69 | NR2E1 (0.61) | NPBWR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL13533794 | 0.69 | NPC1 (0.60) | NPBWR1NPC1RAB9APKMSMN1; SMN2 | |
| SCHEMBL21976216 | 0.67 | ALOX5 (0.65) | NPBWR1NPC1RAB9APKMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7279599 | 0.67 | ALDH1A1 (0.51) | NPBWR1NPC1RAB9APKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2880038-B1 | PROTEIN KINASE INHIBITORS | ASTAR BIOTECH LLC (US) | 2018-05-16 | — | — | EP | disclosed |