Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 5/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | GPR183 | P32249 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 3/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23051561 | 0.89 | GPR119 (0.41) | SCD5GPR119CYP11B2ACACBGPR183 | |
| SCHEMBL23051645 | 0.86 | SCD5 (0.49) | SCD5GPR119CYP11B2ACACBHDAC2 | |
| SCHEMBL23051643 | 0.84 | GPR119 (0.46) | SCD5GPR119CYP11B2ACACBHDAC2 | |
| SCHEMBL23887653 | 0.83 | NR1H2 (0.58) | SCD5GPR119CYP11B2ACACBHDAC2 | |
| SCHEMBL6114652 | 0.80 | CYP11B2 (0.49) | SCD5GPR119CYP11B2ACACBHDAC2 | |
| SCHEMBL21084116 | 0.80 | PKM (0.45) | SCD5GPR119CYP11B2ACACBHDAC2 | |
| SCHEMBL21124030 | 0.80 | PKM (0.45) | SCD5GPR119CYP11B2ACACBHDAC2 | |
| SCHEMBL23565946 | 0.80 | PKM (0.45) | SCD5GPR119CYP11B2ACACBHDAC2 | |
| SCHEMBL34461157 | 0.80 | GPR119 (0.48) | SCD5GPR119CYP11B2ACACBHDAC2 | |
| SCHEMBL30695739 | 0.80 | GPR119 (0.48) | SCD5GPR119CYP11B2ACACBHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021041664-A1 | CEREBLON E3 LIGASE INHIBITORS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2021-03-04 | — | — | WO | disclosed |