SCHEMBL2305262

SCHEMBL2305262

NC(=O)CC[C@H](N)C(=O)OCCS

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.50
BLM P54132 1/20 0.50
PMP22 Q01453 1/20 0.50
KMT2A Q03164 1/20 0.50
DPP4 P27487 1/20 0.38
DPP8 Q6V1X1 1/20 0.38
DPP9 Q86TI2 1/20 0.38
ANPEP P15144 3/20 0.34
ENPEP Q07075 3/20 0.34
NOD1 Q9Y239 1/20 0.33
GRM8 O00222 1/20 0.33
GRM6 O15303 1/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GSR P00390 1/20 0.33
CYP1A2 P05177 1/20 0.33
GRIK1 P39086 1/20 0.33
GRM5 P41594 1/20 0.33
GRIA1 P42261 1/20 0.33
GRIA2 P42262 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8009500 0.86 ALOX15 (0.56) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL398286 0.82 ALOX15 (0.52) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL28643800 0.81 KMT2A (0.50) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL28975260 0.80 SLC1A1 (0.46) KMT2AANPEPENPEPNOD1SLC1A1
SCHEMBL990705 0.80 BLM (0.46) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL28975258 0.80 SLC1A1 (0.46) KMT2AANPEPENPEPNOD1SLC1A1
SCHEMBL4465007 0.79 ALOX15 (0.48) ALOX15BLMPMP22KMT2ADPP4
Hydrochloric Acid SCHEMBL4560462 0.79 BLM (0.44) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL8581073 0.78 NOD1 (0.49) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL8749113 0.78 NOD1 (0.49) ALOX15BLMPMP22KMT2ADPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210348107-A1 DEVICE AND SYSTEMS COMPRISING ELECTRODE ARRAYS FOR ELECTROCONDUCTIVE CELLS UNIVERSITY OF WASHINGTON (US) 2021-11-11 US disclosed
EP-3853342-A1 DEVICE AND SYSTEMS COMPRISING ELECTRODE ARRAYS FOR ELECTROCONDUCTIVE CELLS University of Washington (US) 2021-07-28 EP disclosed
WO-2020061364-A1 DEVICE AND SYSTEMS COMPRISING ELECTRODE ARRAYS FOR ELECTROCONDUCTIVE CELLS UNIVERSITY OF WASHINGTON (US) 2020-03-26 WO disclosed
US-10206940-B2 Nicotinoyl riboside compositions and methods of use CORNELL UNIVERSITY (US) 2019-02-19 US disclosed
CN-108004203-A A kind of culture medium and its method for induced multi-potent stem cell 广东艾时代生物科技有限责任公司 2018-05-08 CN disclosed
US-20160310517-A1 NICOTINOYL RIBOSIDE COMPOSITIONS AND METHODS OF USE CORNELL UNIVERSITY 2016-10-27 US disclosed
WO-2016076435-A1 SCREENING METHOD USING INDUCED NEURONS 国立大学法人京都大学 2016-05-19 WO disclosed
WO-2014148646-A1 PLURIPOTENT STEM CELL FOR NEURONAL DIFFERENTIATION INDUCTION 国立大学法人京都大学 (JP) 2014-09-25 WO disclosed
US-20140205593-A1 MONOVALENT ANTIBODY FRAGMENTS USEFUL AS THERAPEUTICS GENENTECH, INC. (US) 2014-07-24 US disclosed
CN-103710301-A Application of mouse embryo liver stroma cell KM3 as human embryo stem cell feeder layer cell UNIV JIANGSU 2014-04-09 CN disclosed
WO-2011102444-A1 METHOD FOR PRODUCING INDUCED PLURIPOTENT STEM CELLS 国立大学法人大阪大学 (JP) 2011-08-25 WO disclosed
US-20110200596-A1 MONOVALENT ANTIBODY FRAGMENTS USEFUL AS THERAPEUTICS GENENTECH, INC. (US) 2011-08-18 US disclosed
CN-1298843-C Human embryonic stem cells culture medium without dependent feeding cell TAIHE HOSPITAL SHIYAN (CN) 2007-02-07 CN disclosed
CN-1657610-A Human embryonic stem cells culture medium without dependent feeding cell TAIHE HOSPITAL SHIYAN (CN) 2005-08-24 CN disclosed
CN-1655814-A Selective antibody of tumor necrosis factor related apoptosis inducing ligand receptor and use thereof UAB RESEARCH FOUNDATION (US) 2005-08-17 CN disclosed
CN-1630516-A Combinations of antibodies selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and other therapeutic agents UAB RESEARCH FOUNDATION (US) 2005-06-22 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160310517-A1 NICOTINOYL RIBOSIDE COMPOSITIONS AND METHODS OF USE NADK, NNT, CD38 ALOX15 2436/4885BLM 3901/4885PMP22 1513/4885
US-10206940-B2 Nicotinoyl riboside compositions and methods of use NADK, NNT, CD38 ALOX15 2436/4885BLM 3901/4885PMP22 1513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.