Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23058738 | 0.80 | PPARA (0.50) | — | |
| SCHEMBL23058476 | 0.79 | NPSR1 (0.36) | GAANPSR1 | |
| SCHEMBL23058147 | 0.77 | THRA (0.33) | — | |
| SCHEMBL23058181 | 0.73 | PDE2A (0.39) | — | |
| SCHEMBL23058728 | 0.72 | PDE2A (0.44) | — | |
| SCHEMBL23058746 | 0.72 | L3MBTL1 (0.44) | GAAL3MBTL1 | |
| SCHEMBL23058148 | 0.72 | MAPT (0.35) | — | |
| SCHEMBL23058793 | 0.69 | LMNA (0.38) | — | |
| SCHEMBL23058742 | 0.68 | FAAH (0.38) | GAA | |
| SCHEMBL21281427 | 0.65 | SPHK2 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021041588-A1 | SUBSTITUTED PYRIDOPYRIMIDINONYL COMPOUNDS USEFUL AS T CELL ACTIVATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-03-04 | — | — | WO | disclosed |