Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | GGT1 | P19440 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RGS4 | P49798 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23063244 | 0.77 | MAPT (0.46) | KDM4EMAPTKMT2ASIGMAR1ALDH1A1 | |
| SCHEMBL7268077 | 0.74 | CYP1A2 (0.54) | ALDH1A1LMNAPOLBPKMTP53 | |
| SCHEMBL2900381 | 0.73 | PKM (0.83) | ALDH1A1SMN1; SMN2POLBGAAPKM | |
| SCHEMBL10992447 | 0.73 | LMNA (0.51) | KDM4EMAPTKMT2AALDH1A1LMNA | |
| SCHEMBL10738287 | 0.70 | BCHE (0.49) | MAPTKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL18715600 | 0.69 | PKM (0.73) | ALDH1A1LMNASMN1; SMN2GAAPKM | |
| SCHEMBL15423745 | 0.69 | PKM (0.73) | KDM4EMAPTLMNASMN1; SMN2GAA | |
| SCHEMBL20129486 | 0.69 | PKM (0.73) | KDM4EMAPTLMNASMN1; SMN2GAA | |
| SCHEMBL23063513 | 0.69 | ALDH1A1 (0.53) | KDM4EMAPTP2RX4SIGMAR1ALDH1A1 | |
| Anisole SCHEMBL22187427 | 0.68 | ALDH1A1 (0.67) | ALDH1A1POLBGAAEGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3788041-A1 | NOVEL COMPOUNDS | Inflazome Limited (IE) | 2021-03-10 | — | — | EP | disclosed |