Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 8/20 | 0.40 |
| ▸ | HTR2B | P41595 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28030092 | 0.77 | ADRB1 (0.58) | HTR1ASLC6A2SLC6A4ADRB1ADRA1B | |
| SCHEMBL8291557 | 0.75 | ADRB1 (0.61) | HTR1ASLC6A2SLC6A4HPGDADRB1 | |
| Hydrochloric Acid SCHEMBL5766987 | 0.75 | ADRB1 (0.56) | HTR1AHTR2CHTR2BADRB1ADRA1B | |
| Hydrochloric Acid SCHEMBL7836810 | 0.74 | HTR1A (0.59) | HTR1ASLC6A2SLC6A4HTR2CHPGD | |
| SCHEMBL28030551 | 0.73 | MEN1 (0.41) | HTR1ASLC6A2SLC6A4KMT2ASMN1; SMN2 | |
| SCHEMBL28290840 | 0.73 | HTR6 (0.39) | HTR1ASLC6A2SLC6A4ADRB1HTR6 | |
| SCHEMBL10873929 | 0.73 | MGLL (0.37) | HTR1AHTR2BADRB1HTR6ALOX5 | |
| SCHEMBL28030529 | 0.73 | ADRB1 (0.56) | HTR1AHPGDKMT2ASMN1; SMN2ADRB1 | |
| SCHEMBL31198346 | 0.72 | KEAP1 (0.48) | HTR1ASLC6A2SLC6A4KMT2AHCAR1 | |
| SCHEMBL23064483 | 0.72 | KEAP1 (0.48) | HTR1ASLC6A2SLC6A4KMT2AHCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3788042-A1 | BCL-2 INHIBITORS | BeiGene, Ltd. (KY) | 2021-03-10 | — | — | EP | disclosed |