Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 4/20 | 0.34 |
| ▸ | HTR3A | P46098 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | HTR5A | P47898 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10873929 | 0.77 | MGLL (0.37) | HTR6MGLLADRB1HTR1AHTR3A | |
| SCHEMBL28030529 | 0.77 | ADRB1 (0.56) | MGLLADRB1HTR1AHTR3AHTR7 | |
| SCHEMBL28030551 | 0.77 | MEN1 (0.41) | MGLLADRB1HTR1AHTR7ALOX5 | |
| SCHEMBL28030092 | 0.77 | ADRB1 (0.58) | MGLLADRB1HTR1AHTR3AALOX5 | |
| Hydrochloric Acid SCHEMBL5766987 | 0.76 | ADRB1 (0.56) | MGLLADRB1HTR1AHTR3AHTR2A | |
| SCHEMBL28290905 | 0.74 | ALOX5 (0.59) | MGLLADRB1HTR1AHTR2AALOX5 | |
| SCHEMBL28030099 | 0.74 | HTR6 (0.59) | HTR6HTR1AHTR3AHTR2AHTR7 | |
| SCHEMBL23064494 | 0.73 | HTR1A (0.42) | HTR6ADRB1HTR1AHTR2AALOX5 | |
| SCHEMBL28030100 | 0.73 | NCF1 (0.46) | HTR6ADRB1HTR1AHTR2AALOX5 | |
| SCHEMBL28290843 | 0.73 | FAAH (0.42) | HTR6MGLLADRB1HTR3AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025243042-A1 | COMPOUNDS FOR THE INHIBITION OF CYCLOPHILIN D | THE UNIVERSITY OF LIVERPOOL (GB) | 2025-11-27 | — | — | WO | disclosed |
| CN-106061950-B | The manufacturing method of pyrazole compound | 住友化学株式会社 | 2019-05-03 | — | — | CN | disclosed |