Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | FPR2 | P25090 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26897335 | 1.00 | HDAC1 (0.45) | HDAC1HDAC6CTSSCTSKMME | |
| SCHEMBL13630710 | 0.86 | ESR1 (0.46) | CTSSCTSKMMEKMT2ASMN1; SMN2 | |
| SCHEMBL12250692 | 0.86 | ATM (0.43) | MMEMEN1KMT2ANPC1RAB9A | |
| SCHEMBL12250708 | 0.86 | ESR1 (0.46) | CTSSCTSKMMEKMT2ASMN1; SMN2 | |
| SCHEMBL10061085 | 0.86 | ATM (0.43) | MMEMEN1KMT2ANPC1RAB9A | |
| SCHEMBL26417010 | 0.86 | ATM (0.43) | MMEMEN1KMT2ANPC1RAB9A | |
| SCHEMBL12250719 | 0.86 | ESR1 (0.46) | CTSSCTSKMMEKMT2ASMN1; SMN2 | |
| SCHEMBL23974737 | 0.84 | LOXL2 (0.40) | HDAC6MMESMN1; SMN2 | |
| SCHEMBL14011032 | 0.84 | NOS2 (0.45) | CTSSCTSK | |
| SCHEMBL12250727 | 0.84 | NOS2 (0.45) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382950-A1 | CYCLIC APELIN RECEPTOR AGONISTS | HEPTARES THERAPEUTICS LIMITED (GB) | 2023-11-30 | — | — | US | disclosed |
| US-20230382950-A1 | CYCLIC APELIN RECEPTOR AGONISTS | HEPTARES THERAPEUTICS LIMITED (GB) | 2023-11-30 | — | — | US | disclosed |
| US-20230382949-A1 | LINEAR APELIN RECEPTOR AGONISTS | HEPTARES THERAPEUTICS LIMITED (GB) | 2023-11-30 | — | — | US | disclosed |
| US-20230382949-A1 | LINEAR APELIN RECEPTOR AGONISTS | HEPTARES THERAPEUTICS LIMITED (GB) | 2023-11-30 | — | — | US | disclosed |
| US-20230152316-A1 | SARS-COV2 SPIKE PROTEIN BINDING PEPTIDES | MASSACHUSETTS INST TECHNOLOGY (US) | 2023-05-18 | — | — | US | disclosed |
| US-20210060121-A1 | NOVEL ANTIBIOTICS AND METHODS OF USING THEM | VERSITECH LIMITED (CN) | 2021-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382950-A1 | CYCLIC APELIN RECEPTOR AGONISTS | APLNR, MTNR1A, EDNRA | HDAC1 2075/4885HDAC6 3711/4885CTSS 4611/4885 |
| US-20210060121-A1 | NOVEL ANTIBIOTICS AND METHODS OF USING THEM | VIP, TLR5, TREH | HDAC1 2988/4885HDAC6 222/4885CTSS 1813/4885 |
| US-20230382949-A1 | LINEAR APELIN RECEPTOR AGONISTS | APLNR, MTNR1A, EDNRA | HDAC1 3320/4885HDAC6 4165/4885CTSS 4649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.