SCHEMBL2308340

SCHEMBL2308340

IC/C=C/c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.58
PAM P19021 1/20 0.52
MAOB P27338 2/20 0.50
HTR2A P28223 3/20 0.48
SIGMAR1 Q99720 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
KDM4E B2RXH2 1/20 0.42
NFE2L2 Q16236 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1172825 1.00 IDO1 (0.58) IDO1PAMMAOBHTR2ASIGMAR1
SCHEMBL4863423 0.80 IDO1 (0.58) IDO1PAMMAOBHTR2ANPC1
SCHEMBL9777486 0.80 IDO1 (0.58) IDO1PAMMAOBHTR2ANPC1
SCHEMBL2064116 0.80 SIGMAR1 (0.48) IDO1PAMMAOBHTR2ASIGMAR1
SCHEMBL97891 0.79 PAM (0.58) IDO1PAMMAOBHTR2A
SCHEMBL97892 0.79 PAM (0.58) IDO1PAMMAOBHTR2A
SCHEMBL7385940 0.79 PAM (0.58) IDO1PAMMAOBHTR2A
SCHEMBL15302084 0.78 IDO1 (0.47) IDO1PAMMAOBHTR2ASIGMAR1
SCHEMBL73341 0.78 IDO1 (0.47) IDO1PAMMAOBHTR2ASIGMAR1
SCHEMBL5411876 0.78 HTR2A (0.48) IDO1PAMMAOBHTR2ASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6602952-B1 Hydrogels, which are cross-linked polymers that swell in water, have potential as drug delivery vehicles SHEARWATER CORPORATION 2003-08-05 US claimed
JP-2003503367-A 2003-01-28 JP claimed
EP-1223986-A2 HYDROGELS DERIVED FROM CHITOSAN AND POLY(ETHYLENE GLYCOL) Shearwater Corporation (US) 2002-07-24 EP claimed
WO-2001000246-A2 HYDROGELS DERIVED FROM CHITOSAN AND POLY(ETHYLENE GLYCOL) SHEARWATER CORPORATION (US) 2001-01-04 WO claimed
EP-0881205-A1 Method for production of allyloxystyrene compounds LOCTITE CORPORATION (US) 1998-12-02 EP claimed
US-5633411-A Method for production of allyloxystyrene compounds LOCTITE CORPORATION (US) 1997-05-27 US claimed
US-5250393-A Containing diazo resin and alkali metal or ammonium silicate FUJI PHOTO FILM CO., LTD. (JP) 1993-10-05 US claimed
CN-118702853-A Method for terminating anion polymerization and removing initiator 青岛玄道科技有限公司 2024-09-27 CN disclosed
US-11685702-B2 Method for producing arene compounds and arene compounds produced by the same JSI SILICONE CO. (KR) 2023-06-27 US disclosed
US-11565995-B2 Methods of forming imines, imine-related and imine-derived compounds using green solvents THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2023-01-31 US disclosed
US-20210323911-A1 METHODS OF FORMING IMINES, IMINE-RELATED AND IMINE-DERIVED COMPOUNDS USING GREEN SOLVENTS THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK 2021-10-21 US disclosed
US-20210188739-A1 METHOD FOR PRODUCING ARENE COMPOUNDS AND ARENE COMPOUNDS PRODUCED BY THE SAME JSI SILICONE CO. (KR) 2021-06-24 US disclosed
EP-3353167-B1 MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE GLAXOSMITHKLINE IP NO 2 LTD (GB) 2020-06-24 EP disclosed
WO-1999010338-A2 BENZYLIDENE- AND CINNAMYLIDENE-ANABASEINES AS NEURONAL NICOTINIC ALPHA-7 RECEPTOR AGONISTS UNIVERSITY OF FLORIDA (US) 1999-03-04 WO disclosed
EP-0881205-A1 Method for production of allyloxystyrene compounds LOCTITE CORPORATION (US) 1998-12-02 EP disclosed
US-5633411-A Method for production of allyloxystyrene compounds LOCTITE CORPORATION (US) 1997-05-27 US disclosed
US-4025695-A LAMINATION EXXON RESEARCH AND ENGINEERING COMPANY (US) 1977-05-24 US disclosed
US-3985832-A BY REACTING CHLORINATED RUBBER WITH A BROMINE OR IODINE COMPOUND EXXON RESEARCH AND ENGINEERING COMPANY (US) 1976-10-12 US disclosed
US-3976640-A CYANINE POLAROID CORPORATION (US) 1976-08-24 US disclosed
US-3968094-A Photodegradable plastics containing haloolefins THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF AGRICULTURE (US) 1976-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210188739-A1 METHOD FOR PRODUCING ARENE COMPOUNDS AND ARENE COMPOUNDS PRODUCED BY THE SAME PFAS, FRK, AGPAT2 IDO1 2819/4885PAM 835/4885MAOB 781/4885
US-11685702-B2 Method for producing arene compounds and arene compounds produced by the same PFAS, FRK, AGPAT2 IDO1 2819/4885PAM 835/4885MAOB 781/4885
US-20210323911-A1 METHODS OF FORMING IMINES, IMINE-RELATED AND IMINE-DERIVED COMPOUNDS USING GREEN SOLVENTS IK, LDHB, IDH3B IDO1 30/4885PAM 1421/4885MAOB 631/4885
US-11565995-B2 Methods of forming imines, imine-related and imine-derived compounds using green solvents IK, LDHB, IDH3B IDO1 30/4885PAM 1421/4885MAOB 631/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.