SCHEMBL73341

SCHEMBL73341

Cl[SiH](Cl)CC=Cc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.47
PAM P19021 1/20 0.47
MAOB P27338 2/20 0.44
HTR2A P28223 3/20 0.44
KDM4E B2RXH2 1/20 0.43
SIGMAR1 Q99720 2/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
NFE2L2 Q16236 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15302530 0.83 HTR2A (0.46) IDO1PAMMAOBHTR2AKDM4E
SCHEMBL15302418 0.79 HTR2A (0.43) IDO1PAMMAOBHTR2AKDM4E
SCHEMBL1172825 0.78 IDO1 (0.58) IDO1PAMMAOBHTR2AKDM4E
SCHEMBL2308340 0.78 IDO1 (0.58) IDO1PAMMAOBHTR2AKDM4E
SCHEMBL15302084 0.77 IDO1 (0.47) IDO1PAMMAOBHTR2AKDM4E
SCHEMBL5411876 0.77 HTR2A (0.48) IDO1PAMMAOBHTR2AKDM4E
SCHEMBL15303036 0.77 IDO1 (0.47) IDO1PAMMAOBHTR2AKDM4E
SCHEMBL3620068 0.77 PAM (0.52) IDO1PAMMAOBHTR2AKDM4E
SCHEMBL15302218 0.77 HTR2A (0.41) IDO1PAMMAOBHTR2AKDM4E
SCHEMBL4863423 0.75 IDO1 (0.58) IDO1PAMMAOBHTR2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100190637-A1 Curing Catalyst MERCK PATENT GESELLSCHAFT (DE) 2010-07-29 US claimed
US-6046293-A Solid-liquid phase interfacial polymerization UNIVERSITY OF SOUTH AUSTRALIA (AU) 2000-04-04 US claimed
EP-0799851-A2 Preparation of polyorganosilloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-10-08 EP claimed
US-5629401-A Preparation of polyorganosiloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-05-13 US claimed
US-20260007589-A1 METHOD FOR DYEING KERATINOUS MATERIAL COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, AN EFFECT PIGMENT, AND A FILM-FORMING POLYMER III HENKEL AG & CO. KGAA (DE) 2026-01-08 US disclosed
US-12485077-B2 Method for dyeing keratinous material, comprising the use of an organosilicon compound, an effect pigment and a post-treatment agent HENKEL AG & CO. KGAA (DE) 2025-12-02 US disclosed
US-12377034-B2 Method for dyeing keratinous material, comprising the use of an organosilicon compound, an effect pigment and a film-forming polymer II HENKEL AG & CO. KGAA (DE) 2025-08-05 US disclosed
US-12357554-B2 Process of coloring keratinous material comprising the use of an organosilicon compound, an effect pigment, and a sealing reagent VI HENKEL AG & CO. KGAA (DE) 2025-07-15 US disclosed
US-12329840-B2 Agent for dyeing keratin material, containing at least two organosilicon compounds that are different from each other, at least one pigment and at least one liquid fatty component and/or a solvent HENKEL AG & CO. KGAA (DE) 2025-06-17 US disclosed
EP-4561706-A1 METHOD FOR DYEING KERATINOUS MATERIAL, INCLUDING THE PROCESS OF TREATING THE KERATINOUS MATERIAL WITH PLASMA AND THE USE OF A DYE Henkel AG & Co. KGaA (DE) 2025-06-04 EP disclosed
EP-4547197-A1 METHOD FOR DYEING KERATINOUS MATERIAL COMPRISING THE LEAVE-ON APPLICATION OF A DYE THAT HAS A LOW WATER CONTENT AND COMPRISES C1-C6 ALKOXY SILANE, PIGMENT AND SOLVENT Henkel AG & Co. KGaA (DE) 2025-05-07 EP disclosed
US-20250107990-A1 Method for Dyeing Keratinous Material Comprising the Leave-On Application of a Dye That Has a Low Water Content and Comprises C1-C6 Alkoxy Silane, Pigment and Solvent HENKEL AG & CO KGAA (DE) 2025-04-03 US disclosed
WO-1997004034-A1 METAL SUBSTRATE WITH ENHANCED CORROSION RESISTANCE AND IMPROVED PAINT ADHESION ARMCO INC. (US) 1997-02-06 WO disclosed
US-5539031-A Metal substrate with enhanced corrosion resistance and improved paint adhesion ARMCO INC. (US) 1996-07-23 US disclosed
US-5498481-A Metal substrate with enhanced corrosion resistance and improved paint adhesion ARMCO INC. (US) 1996-03-12 US disclosed
US-5455080-A Metal substrate with enhanced corrosion resistance and improved paint adhesion ARMCO INC. (US) 1995-10-03 US disclosed
US-5307438-A Index matching compositions with improved DNG/DT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-04-26 US disclosed
EP-0586276-A2 Index matching compositions with improved DNg/DT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-03-09 EP disclosed
US-5155181-A Crosslinking by an energy input; pyrolyze to form a silicon nitride-containing ceramic HERCULES INCORPORATED (US) 1992-10-13 US disclosed
US-4307212-A Curable epoxy resins GENERAL ELECTRIC COMPANY (US) 1981-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12357554-B2 Process of coloring keratinous material comprising the use of an organosilicon compound, an effect pigment, and a sealing reagent VI KRT18, GP6, MSH6 IDO1 2699/4885PAM 4263/4885MAOB 2783/4885
US-12485077-B2 Method for dyeing keratinous material, comprising the use of an organosilicon compound, an effect pigment and a post-treatment agent KRT18, KIT, MSH6 IDO1 3036/4885PAM 2116/4885MAOB 1299/4885
US-12377034-B2 Method for dyeing keratinous material, comprising the use of an organosilicon compound, an effect pigment and a film-forming polymer II KRT18, PDS5B, MSH6 IDO1 2407/4885PAM 4602/4885MAOB 600/4885
US-20260007589-A1 METHOD FOR DYEING KERATINOUS MATERIAL COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, AN EFFECT PIGMENT, AND A FILM-FORMING POLYMER III KRT18, GP6, F12 IDO1 2866/4885PAM 4642/4885MAOB 1785/4885
US-20250107990-A1 Method for Dyeing Keratinous Material Comprising the Leave-On Application of a Dye That Has a Low Water Content and Comprises C1-C6 Alkoxy Silane, Pigment and Solvent KRT18, ALG3, MKI67 IDO1 733/4885PAM 3873/4885MAOB 2337/4885
US-12329840-B2 Agent for dyeing keratin material, containing at least two organosilicon compounds that are different from each other, at least one pigment and at least one liquid fatty component and/or a solvent KRT18, CUTA, DSG1 IDO1 1476/4885PAM 4072/4885MAOB 3121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.