SCHEMBL2310066

SCHEMBL2310066

COCC(N)(COC)COC

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SPHK2 Q9NRA0 2/20 0.33
SPHK1 Q9NYA1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15648240 0.83
SCHEMBL15218488 0.83
SCHEMBL2568929 0.81 MEN1 (0.50) SPHK2SPHK1
SCHEMBL1945695 0.81
SCHEMBL15237277 0.81
SCHEMBL9778987 0.77 ALDH1A1 (0.39)
SCHEMBL13004398 0.74
Hydrochloric Acid SCHEMBL5717300 0.74 SPHK2 (0.31) SPHK2SPHK1
SCHEMBL56461 0.74
SCHEMBL56781 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024056805-A1 NEW PET TRACER FOR IMAGING OF THE FUNCTIONAL HEPATIC RESERVE MEDIZINISCHE UNIVERSITÄT INNSBRUCK (AT) 2024-03-21 WO disclosed
US-20200368173-A1 NUCLEIC ACID-CONTAINING LIPID NANOPARTICLE KYOWA KIRIN CO., LTD. (JP) 2020-11-26 US disclosed
EP-3137115-B1 METHOD FOR SYNTHESIS OF REACTIVE CONJUGATE CLUSTERS IONIS PHARMACEUTICALS INC (US) 2020-10-14 EP disclosed
US-9850147-B2 Functional polymer membrane and method of producing the same FUJIFILM CORPORATION (JP) 2017-12-26 US disclosed
EP-2902097-B1 FUNCTIONAL POLYMER MEMBRANE AND METHOD FOR ITS PRODUCTION FUJIFILM CORP (JP) 2017-11-29 EP disclosed
EP-2896636-B1 CURABLE COMPOSITION AND IMAGE-FORMING METHOD FUJIFILM CORP (JP) 2017-09-27 EP disclosed
EP-2350077-B1 FUSED, SPIROCYCLIC HETEROAROMATIC COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS ENTASIS THERAPEUTICS LTD (GB) 2016-01-27 EP disclosed
US-20150368266-A1 CHEMICAL COMPOUNDS 542 ENTASIS THERAPEUTICS INC. 2015-12-24 US disclosed
US-9139747-B2 Image forming method FUJIFILM CORPORATION (JP) 2015-09-22 US disclosed
US-20150259227-A1 FUNCTIONAL POLYMER MEMBRANE AND METHOD OF PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2015-09-17 US disclosed
US-20150191613-A1 INK COMPOSITION, INK SET, AND IMAGE FORMATION METHOD FUJIFILM CORPORATION (JP) 2015-07-09 US disclosed
US-9040528-B2 Chemical compounds 542 ASTRAZENECA AB (SE) 2015-05-26 US disclosed
US-20140128371-A1 CHEMICAL COMPOUNDS 542 ASTRAZENECA AB (SE) 2014-05-08 US disclosed
US-8658641-B2 Fused, spirocyclic heteroaromatic compounds for the treatment of bacterial infections ASTRAZENECA AB (SE) 2014-02-25 US disclosed
US-20130222501-A1 IMAGE FORMING METHOD FUJIFILM CORPORATION (JP) 2013-08-29 US disclosed
US-20110245224-A1 FUSED, SPIROCYCLIC HETEROAROMATIC COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS ASTRAZENECA AB (SE) 2011-10-06 US disclosed
EP-2350077-A1 FUSED, SPIROCYCLIC HETEROAROMATIC COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS AstraZeneca AB (SE) 2011-08-03 EP disclosed
WO-2010043893-A1 FUSED, SPIROCYCLIC HETEROAROMATIC COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS ASTRAZENECA AB (SE) 2010-04-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150368266-A1 CHEMICAL COMPOUNDS 542 MRPL21, CFTR, CYP3A43 SPHK2 2459/4885SPHK1 3323/4885
US-20110245224-A1 FUSED, SPIROCYCLIC HETEROAROMATIC COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS SDHB, SDHA, RORC SPHK2 1963/4885SPHK1 2015/4885
US-20200368173-A1 NUCLEIC ACID-CONTAINING LIPID NANOPARTICLE LIPA, LIPC, PNLIP SPHK2 1541/4885SPHK1 1300/4885
US-20140128371-A1 CHEMICAL COMPOUNDS 542 MRPL21, CFTR, CYP3A43 SPHK2 2459/4885SPHK1 3323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.