SCHEMBL2310464

SCHEMBL2310464

CCOC(=O)c1ccccc1NC(=O)c1ccccc1NS(=O)(=O)c1ccc2ccccc2c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.67
KDM4E B2RXH2 4/20 0.67
HSD17B10 Q99714 2/20 0.67
LMNA P02545 7/20 0.65
HTT P42858 4/20 0.64
ALDH1A1 P00352 4/20 0.64
TDP1 Q9NUW8 4/20 0.64
SMN1; SMN2 Q16637 3/20 0.64
HPGD P15428 2/20 0.64
TP53 P04637 2/20 0.64
NPC1 O15118 1/20 0.64
GAA P10253 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
KMT2A Q03164 2/20 0.64
MAPT P10636 2/20 0.56
MAPK1 P28482 2/20 0.53
RAB9A P51151 1/20 0.53
NPSR1 Q6W5P4 3/20 0.53
POLB P06746 2/20 0.51
HIF1A Q16665 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14855615 0.87 LMNA (0.86) TSHRKDM4EHSD17B10LMNAHTT
SCHEMBL18151726 0.81 KMT2A (0.67) TSHRKDM4ELMNAHTTALDH1A1
SCHEMBL27939522 0.81 HIF1A (0.55) TSHRKDM4ELMNAHTTALDH1A1
SCHEMBL14855684 0.81 TSHR (1.00) TSHRKDM4EHSD17B10LMNAHTT
SCHEMBL26188511 0.79 LMNA (0.81) TSHRKDM4EHSD17B10LMNAHTT
SCHEMBL7572290 0.79 LMNA (0.72) TSHRKDM4EHSD17B10LMNAHTT
SCHEMBL23200329 0.78 KDM4E (0.64) TSHRKDM4EHSD17B10LMNAHTT
SCHEMBL7320847 0.77 PKM (0.64) KDM4ELMNAHTTALDH1A1TDP1
SCHEMBL27880210 0.76 RAB9A (0.55) TSHRKDM4EHSD17B10SMN1; SMN2HPGD
SCHEMBL7370095 0.76 TSHR (0.77) TSHRKDM4EHSD17B10LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2531570-B1 BLUEGREEN FLUORESCENT COMPOUNDS HONEYWELL INT INC (US) 2017-05-31 EP claimed
EP-2531570-B1 BLUEGREEN FLUORESCENT COMPOUNDS HONEYWELL INT INC (US) 2017-05-31 EP disclosed
US-8664425-B2 Bluegreen fluorescent compounds HONEYWELL INTERNATIONAL INC. (US) 2014-03-04 US disclosed
EP-2531570-A2 BLUEGREEN FLUORESCENT COMPOUNDS Honeywell International Inc. (US) 2012-12-12 EP disclosed
WO-2011097145-A2 BLUEGREEN FLUORESCENT COMPOUNDS HONEYWELL INTERNATIONAL INC. (US) 2011-08-11 WO disclosed
US-20110190528-A1 BLUEGREEN FLUORESCENT COMPOUNDS HONEYWELL INTERNATIONAL INC. (US) 2011-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110190528-A1 BLUEGREEN FLUORESCENT COMPOUNDS MAPT, MPST, TST TSHR 3035/4885KDM4E 504/4885HSD17B10 2538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.