Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TYR | P14679 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.57 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.57 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.57 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.57 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.57 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047674 | 0.85 | KMT2A (0.76) | KMT2ACYP1A2ALDH1A1TP53TYR | |
| SCHEMBL28879854 | 0.84 | TAS2R38 (0.57) | KMT2ACYP1A2ALDH1A1SIGMAR1TAS2R38 | |
| SCHEMBL5442377 | 0.83 | CA12 (0.66) | KMT2ACYP1A2ALDH1A1SIGMAR1TAS2R38 | |
| SCHEMBL5180715 | 0.80 | SIGMAR1 (0.57) | ALDH1A1SIGMAR1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL1184711 | 0.80 | SIGMAR1 (0.57) | KMT2ACYP1A2SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL220272 | 0.79 | ALDH1A1 (0.48) | KMT2ACYP1A2ALDH1A1TP53TYR | |
| SCHEMBL28936790 | 0.78 | KMT2A (0.66) | KMT2ACYP1A2ALDH1A1TP53TYR | |
| SCHEMBL29654010 | 0.78 | KMT2A (0.66) | KMT2ACYP1A2ALDH1A1TP53TYR | |
| SCHEMBL1884582 | 0.78 | KMT2A (1.00) | KMT2ACYP1A2ALDH1A1SIGMAR1TP53 | |
| SCHEMBL4174363 | 0.77 | CA12 (0.55) | KMT2ACYP1A2ALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103450112-B | A kind of nitrogenous five member ring heterocyclic compound that N- bridging connects and its preparation and purposes | 华东理工大学 | 2019-09-13 | — | — | CN | disclosed |
| US-8877908-B2 | Stimulus-responsive apta chelamers | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2014-11-04 | — | — | US | disclosed |
| US-8877908-B2 | Stimulus-responsive apta chelamers | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2014-11-04 | — | — | US | disclosed |
| CN-103450112-A | N-bridge connected nitrogenous five-membered heterocyclic compound and preparation and application thereof | UNIV EAST CHINA SCIENCE & TECH | 2013-12-18 | — | — | CN | disclosed |
| US-20110190483-A1 | Stimulus-Responsive Apta Chelamers | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2011-08-04 | — | — | US | disclosed |
| US-20110190483-A1 | Stimulus-Responsive Apta Chelamers | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2011-08-04 | — | — | US | disclosed |
| WO-2010006238-A2 | STIMULUS-RESPONSIVE APTA-CHELAMERS | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2010-01-14 | — | — | WO | disclosed |
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | ARENA PHARMACEUTICALS, INC. | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | MCHR1, GPR119, MCHR2 | KMT2A 792/4885CYP1A2 407/4885ALDH1A1 2069/4885 |
| US-20110190483-A1 | Stimulus-Responsive Apta Chelamers | CNBP, CREB1, ATF4 | KMT2A 3080/4885CYP1A2 4878/4885ALDH1A1 4702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.