Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 5/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 7/20 | 0.40 |
| ▸ | CASP7 | P55210 | 7/20 | 0.40 |
| ▸ | CASP9 | P55211 | 3/20 | 0.40 |
| ▸ | BACE1 | P56817 | 3/20 | 0.40 |
| ▸ | GNPAT | O15228 | 1/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.38 |
| ▸ | CASP4 | P49662 | 2/20 | 0.38 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.38 |
| ▸ | CASP10 | Q92851 | 2/20 | 0.37 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23133189 | 1.00 | CASP1 (0.49) | CASP1OPRD1CASP3CASP7CASP9 | |
| SCHEMBL20257125 | 1.00 | CASP1 (0.49) | CASP1OPRD1CASP3CASP7CASP9 | |
| SCHEMBL20257122 | 1.00 | CASP1 (0.49) | CASP1OPRD1CASP3CASP7CASP9 | |
| SCHEMBL2556937 | 0.92 | CASP1 (0.47) | CASP1CASP3 | |
| SCHEMBL7286925 | 0.92 | CASP1 (0.47) | CASP1CASP3 | |
| SCHEMBL5085996 | 0.92 | CASP1 (0.47) | CASP1CASP3 | |
| SCHEMBL2556934 | 0.92 | CASP1 (0.47) | CASP1CASP3 | |
| SCHEMBL4100803 | 0.87 | CASP1 (0.50) | CASP1CASP3CASP7CASP9BACE1 | |
| SCHEMBL29310042 | 0.87 | CASP1 (0.50) | CASP1CASP3CASP7CASP9BACE1 | |
| SCHEMBL13194679 | 0.87 | CASP1 (0.50) | CASP1CASP3CASP7CASP9BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210088504-A1 | PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF | TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) | 2021-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210088504-A1 | PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF | SENP8, SENP6, SENP7 | CASP1 1744/4885OPRD1 4450/4885CASP3 2987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.