Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23138146 | 0.75 | ALDH1A1 (0.36) | MAPK1ALDH1A1LMNAL3MBTL1NSD2 | |
| SCHEMBL7386352 | 0.71 | RET (0.39) | MAPK1LMNATDP1POLBNPSR1 | |
| SCHEMBL2443752 | 0.68 | GAA (0.46) | MAPK1ALDH1A1LMNAL3MBTL1MAPT | |
| SCHEMBL8927868 | 0.61 | CYP3A4 (0.40) | MAPK1ALDH1A1LMNAL3MBTL1NSD2 | |
| SCHEMBL18984670 | 0.60 | ALDH1A1 (0.50) | MAPK1ALDH1A1LMNAL3MBTL1NSD2 | |
| SCHEMBL3786708 | 0.60 | GAA (0.52) | MAPK1ALDH1A1LMNAL3MBTL1NSD2 | |
| SCHEMBL18874615 | 0.59 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1MAPTTDP1NPSR1 | |
| SCHEMBL12316533 | 0.59 | GFER (0.37) | MAPK1ALDH1A1POLBNPSR1BLM | |
| SCHEMBL23116593 | 0.58 | ATP1A1 (0.40) | MAPK1ALDH1A1LMNAMAPTPOLB | |
| SCHEMBL6790445 | 0.58 | GAA (0.42) | MAPK1L3MBTL1NSD2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11560365-B2 | Non-fluorescent rhodamines | THE UNIVERSITY OF TOKYO (JP) | 2023-01-24 | — | — | US | disclosed |
| US-20210087160-A1 | NOVEL NON-FLUORESCENT RHODAMINES | THE UNIVERSITY OF TOKYO (JP) | 2021-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210087160-A1 | NOVEL NON-FLUORESCENT RHODAMINES | QTRT1, QTRT2, NONO | MAPK1 3022/4885ALDH1A1 4506/4885LMNA 2033/4885 |
| US-11560365-B2 | Non-fluorescent rhodamines | QTRT1, QTRT2, NONO | MAPK1 3042/4885ALDH1A1 4441/4885LMNA 1831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.