Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 5/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18927575 | 0.82 | RIPK1 (0.59) | RIPK1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL23123430 | 0.76 | RIPK1 (0.50) | RIPK1CNR2UTS2RHRH3 | |
| SCHEMBL24700138 | 0.74 | RIPK1 (0.52) | RIPK1CNR2LMNA | |
| SCHEMBL4613765 | 0.73 | RIPK1 (0.48) | RIPK1CNR2UTS2RHRH3 | |
| SCHEMBL18927447 | 0.69 | RIPK1 (0.44) | RIPK1DPP4 | |
| SCHEMBL4392356 | 0.68 | UTS2R (0.49) | RIPK1UTS2R | |
| SCHEMBL18573595 | 0.67 | LMNA (0.55) | LMNA | |
| SCHEMBL18536645 | 0.67 | ITGB1 (0.51) | — | |
| SCHEMBL18927573 | 0.67 | RIPK1 (0.61) | RIPK1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL829416 | 0.67 | RIPK1 (0.53) | RIPK1UTS2RLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021055630-A1 | SUBSTITUTED, SATURATED AND UNSATURATED N-HETEROCYCLIC CARBOXAMIDES AND RELATED COMPOUNDS FOR THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | BIAL- BIOTECH INVESTMENTS, INC. (US) | 2021-03-25 | — | — | WO | disclosed |