Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | AGER | Q15109 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | YAP1 | P46937 | 1/20 | 0.39 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23144533 | 1.00 | CTSD (0.46) | CTSDNPC1RAB9AALDH1A1PAX8 | |
| SCHEMBL23144534 | 1.00 | CTSD (0.46) | CTSDNPC1RAB9AALDH1A1PAX8 | |
| SCHEMBL5378349 | 0.88 | CTSD (0.48) | CTSDALDH1A1SMN1; SMN2HTTAGER | |
| SCHEMBL17314169 | 0.84 | SLC18A3 (0.57) | CTSDNPC1RAB9AALDH1A1PAX8 | |
| SCHEMBL17314167 | 0.84 | SLC18A3 (0.57) | CTSDNPC1RAB9AALDH1A1PAX8 | |
| SCHEMBL17314168 | 0.84 | SLC18A3 (0.57) | CTSDNPC1RAB9AALDH1A1PAX8 | |
| SCHEMBL23144528 | 0.81 | SLC18A3 (0.54) | CTSDNPC1RAB9AALDH1A1PAX8 | |
| SCHEMBL23175993 | 0.79 | AGER (0.63) | NPC1RAB9AALDH1A1PAX8SMN1; SMN2 | |
| SCHEMBL21359110 | 0.79 | CTSD (0.50) | CTSDALDH1A1AGERMEN1KMT2A | |
| SCHEMBL2936216 | 0.77 | OPRM1 (0.58) | CTSDNPC1RAB9AALDH1A1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220387411-A1 | TARGETED AUTOPHAGY CONJUGATES AND METHODS | VULCAN BIO CORPORATION | 2022-12-08 | — | — | US | disclosed |
| US-20220387411-A1 | TARGETED AUTOPHAGY CONJUGATES AND METHODS | VULCAN BIO CORPORATION | 2022-12-08 | — | — | US | disclosed |
| EP-4034557-A1 | TARGETED AUTOPHAGY CONJUGATES AND METHODS | Frontier Medicines Corporation (US) | 2022-08-03 | — | — | EP | disclosed |
| WO-2021061858-A1 | TARGETED AUTOPHAGY CONJUGATES AND METHODS | FRONTIER MEDICINES CORPORATION (US) | 2021-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220387411-A1 | TARGETED AUTOPHAGY CONJUGATES AND METHODS | ATG7, BECN1, SQSTM1 | CTSD 202/4885NPC1 48/4885RAB9A 126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.