Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 1.00 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 1.00 |
| ▸ | HTR3B | O95264 | 3/20 | 1.00 |
| ▸ | HTR3A | P46098 | 3/20 | 1.00 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 1.00 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 1.00 |
| ▸ | HTR2C | P28335 | 2/20 | 1.00 |
| ▸ | HTR1D | P28221 | 1/20 | 1.00 |
| ▸ | THRB | P10828 | 2/20 | 0.97 |
| ▸ | MAPT | P10636 | 1/20 | 0.97 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.69 |
| ▸ | HTR1A | P08908 | 3/20 | 0.57 |
| ▸ | HTR7 | P34969 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6094745 | 1.00 | ALDH1A1 (1.00) | ALDH1A1SIGMAR1HTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL720648 | 0.98 | THRB (1.00) | ALDH1A1SIGMAR1HTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL12818335 | 0.98 | THRB (1.00) | ALDH1A1SIGMAR1HTR3EHTR3BHTR3A | |
| Bromide SCHEMBL9146763 | 0.98 | ALDH1A1 (0.97) | ALDH1A1SIGMAR1HTR3EHTR3BHTR3A | |
| Piperazine SCHEMBL28225297 | 0.97 | THRB (0.97) | ALDH1A1SIGMAR1HTR3EHTR3BHTR3A | |
| SCHEMBL3060543 | 0.94 | ALDH1A1 (0.88) | ALDH1A1SIGMAR1HTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL9311165 | 0.92 | THRB (0.88) | ALDH1A1SIGMAR1HTR3EHTR3BHTR3A | |
| SCHEMBL232665 | 0.90 | ALDH1A1 (0.82) | ALDH1A1SIGMAR1HTR3EHTR3BHTR3A | |
| Hexane SCHEMBL6472819 | 0.90 | ALDH1A1 (0.81) | ALDH1A1SIGMAR1HTR3EHTR3BHTR3A | |
| SCHEMBL31642192 | 0.88 | HTR3E (0.79) | ALDH1A1SIGMAR1HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1915 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250360137-A1 | ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES | FREEDOM BIOSCIENCES INC (US) | 2025-11-27 | — | — | US | claimed |
| EP-4618980-A1 | ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES | Freedom Biosciences, Inc. (US) | 2025-09-24 | — | — | EP | claimed |
| EP-4049017-B1 | APPARATUS AND METHOD FOR DETERMINATION OF BANNED SUBSTANCES | TALLINN UNIV OF TECHNOLOGY (EE) | 2025-03-26 | — | — | EP | claimed |
| US-12111260-B2 | Apparatus and method for determination of banned substances | TALLINN UNIVERSITY OF TECHNOLOGY (EE) | 2024-10-08 | — | — | US | claimed |
| CN-114965780-B | Method for simultaneously measuring 30 mental active substances in environmental water body | 中科检测技术服务(广州)股份有限公司 | 2024-09-24 | — | — | CN | claimed |
| WO-2024107445-A1 | ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES | FREEDOM BIOSCIENCES, INC. (US) | 2024-05-23 | — | — | WO | claimed |
| EP-4049017-A2 | APPARATUS AND METHOD FOR DETERMINATION OF BANNED SUBSTANCES | Tallinn University of Technology (EE) | 2022-08-31 | — | — | EP | claimed |
| US-20220249440-A1 | MUSCLE REGENERATION PROMOTER | SATO PHARMACEUTICAL CO., LTD. (JP) | 2022-08-11 | — | — | US | claimed |
| CN-114773267-A | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2022-07-22 | — | — | CN | claimed |
| CN-114631021-A | Apparatus and method for determining a non-enabling substance | 塔林理工大学 | 2022-06-14 | — | — | CN | claimed |
| EP-0539180-A1 | Antiviral agents | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-04-28 | — | — | EP | claimed |
| US-4742054-A | Treatment of mammals suffering from damage to the central nervous system | NAFTCHI NOSRAT E (US) | 1988-05-03 | — | — | US | claimed |
| EP-0254623-A1 | Aminoalkylthio triazolopyridine or triazoloquinoline derivatives, process for their preparation, medicaments containing them, particularly useful as antalgics | LABORATOIRES UPSA (FR) | 1988-01-27 | — | — | EP | claimed |
| EP-0117531-B1 | N-(3-TRIFLUOROMETHYL PHENYL)-N'-PROPARGYL PIPERAZINE, METHOD FOR ITS PREPARATION AND ITS USE | BOEHRINGER INGELHEIM KG (DE) | 1986-09-17 | — | — | EP | claimed |
| EP-0117531-A1 | N-(3-trifluoromethyl phenyl)-N'-propargyl piperazine, method for its preparation and its use | BOEHRINGER INGELHEIM KG (DE) | 1984-09-05 | — | — | EP | claimed |
| EP-0025985-B1 | 2-SUBSTITUTED TRIAZOLO(4,3-1)PYRIDIN-3(2H)-ONES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF DEPRESSION | Bristol-Myers Company (US) | 1983-11-23 | — | — | EP | claimed |
| EP-0091511-A2 | 1-(3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl)-4-(substituted)-piperazines and -piperidines, a process for the preparation thereof, pharmaceutical compositions containing the same and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1983-10-19 | — | — | EP | claimed |
| EP-0025985-A1 | 2-Substituted triazolo(4,3-1)pyridin-3(2H)-ones, process for their preparation and pharmaceutical compositions for the treatment of depression | Bristol-Myers Company (US) | 1981-04-01 | — | — | EP | claimed |
| US-4203986-A | TRANQUILIZERS, SEDATIVES, ANTITUSSIVE AGNETS | METABIO-JOULLIE (FR) | 1980-05-20 | — | — | US | claimed |
| EP-0008256-A2 | Indane-acetic acid esters, their preparation and medicaments containing them | HEXACHIMIE Société anonyme dite: (FR) | 1980-02-20 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220249440-A1 | MUSCLE REGENERATION PROMOTER | MUSK, MYLK2, MYH2 | ALDH1A1 1317/4885SIGMAR1 1573/4885HTR3E 64/4885 |
| US-20250360137-A1 | ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES | PDE9A, PDE3A, PDE2A | ALDH1A1 1406/4885SIGMAR1 1960/4885HTR3E 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.