SCHEMBL2320568

SCHEMBL2320568

C=COC(=O)CCC(C[N+](C)(C)C)OP(=O)(O)O

nearest known ligand 0.31

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.31
MEN1 O00255 4/20 0.31
KMT2A Q03164 4/20 0.31
CYP2C19 P33261 2/20 0.31
RECQL P46063 1/20 0.31
MAPK1 P28482 4/20 0.31
MAPT P10636 4/20 0.31
GMNN O75496 3/20 0.31
LMNA P02545 3/20 0.31
NPSR1 Q6W5P4 3/20 0.31
TP53 P04637 3/20 0.31
TSHR P16473 3/20 0.31
HSP90AA1 P07900 2/20 0.31
BLM P54132 2/20 0.31
NR1H4 Q96RI1 2/20 0.31
CYP2C9 P11712 2/20 0.31
HIF1A Q16665 2/20 0.31
SLC25A20 O43772 3/20 0.30
CYP2D6 P10635 2/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2321479 0.86 TSHR (0.40) CYP1A2MEN1KMT2ACYP2C19RECQL
SCHEMBL2321002 0.78 SMPD1 (0.30)
SCHEMBL2321681 0.75 TDP1 (0.34) MEN1KMT2A
SCHEMBL7060705 0.74 TSHR (0.39) MAPK1TP53TSHRHIF1ACYP3A4
SCHEMBL170994 0.73 CYP1A2 (0.32) CYP1A2MEN1KMT2ACYP2C19RECQL
SCHEMBL2319797 0.73 ZDHHC20 (0.36) MAPK1TSHR
SCHEMBL3882717 0.72 FAAH (0.33)
SCHEMBL21293806 0.71 LPAR1 (0.33)
SCHEMBL5699819 0.71 FABP3 (0.41) CYP1A2MEN1KMT2ACYP2C19MAPK1
Methacrylic Acid SCHEMBL28639504 0.70 LMNA (0.36) CYP1A2MEN1KMT2AMAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4121802-B1 HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES ALCON INC (CH) 2024-07-17 EP claimed
EP-4076916-B1 WETTABLE SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-06-12 EP claimed
EP-4369081-A2 METHOD FOR PRODUCING AN OPHTHALMIC PRODUCT Alcon Inc. (CH) 2024-05-15 EP claimed
EP-4121801-B1 INSERT MATERIALS WITH HIGH OXYGEN PERMEABILITY AND HIGH REFRACTIVE INDEX ALCON INC (CH) 2024-04-17 EP claimed
EP-4146461-B1 METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-03-13 EP claimed
EP-4118134-B1 PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS ALCON INC (CH) 2024-02-28 EP claimed
US-11867874-B2 Insert materials with high oxygen permeability and high refractive index ALCON INC. (CH) 2024-01-09 US claimed
WO-2023228055-A1 UV/HEVL-FILTERING CONTACT LENSES ALCON INC. (CH) 2023-11-30 WO claimed
US-20230374306-A1 UV/HEVL-FILTERING CONTACT LENSES ALCON INC. (CH) 2023-11-23 US claimed
US-20230364832-A1 METHOD FOR MAKING UV AND HEVL-ABSORBING OPHTHALMIC LENSES ALCON INC. (CH) 2023-11-16 US claimed
EP-3862384-A2 POLYMERIC SUBSTRATE WITH A SURFACE HAVING REDUCED BIOMOLECULE ADHESION, AND THERMOPLASTIC ARTICLES OF SUCH SUBSTRATE SiO2 Medical Products, Inc. (US) 2021-08-11 EP claimed
US-20210181379-A1 WETTABLE SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2021-06-17 US claimed
US-20210132411-A1 CONTACT LENSES WITH SURFACES HAVING DIFFERENT SOFTNESS ALCON INC. (CH) 2021-05-06 US claimed
US-10968319-B2 Silicone hydrogel contact lenses ALCON INC. (CH) 2021-04-06 US claimed
US-10962803-B2 Contact lenses with a lubricious coating thereon ALCON INC. (CH) 2021-03-30 US claimed
US-20200405747-A1 OPHTHALMIC COMPOSITIONS ALCON RESEARCH, LLC 2020-12-31 US claimed
WO-2020261185-A1 OPHTHALMIC COMPOSITIONS ALCON INC. (CH) 2020-12-30 WO claimed
US-20190300654-A1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON RESEARCH, LTD. 2019-10-03 US claimed
US-20190263971-A1 SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2019-08-29 US claimed
US-20190235277-A1 CONTACT LENSES WITH A LUBRICIOUS COATING THEREON ALCON INC. (CH) 2019-08-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200405747-A1 OPHTHALMIC COMPOSITIONS B4GALT1, B3GAT3, ALG1 CYP1A2 3408/4885MEN1 2743/4885KMT2A 4061/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.