SCHEMBL2321115

SCHEMBL2321115

CC(C)(C=O)CN1CCN(CCO)CC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.39
KDM4E B2RXH2 2/20 0.39
LMNA P02545 2/20 0.38
HPGD P15428 2/20 0.38
POLB P06746 2/20 0.38
GAA P10253 1/20 0.38
THRB P10828 1/20 0.38
TSHR P16473 1/20 0.38
KMT2A Q03164 3/20 0.38
HTT P42858 1/20 0.38
ALOX15 P16050 1/20 0.36
ALOX12 P18054 1/20 0.36
HSD17B10 Q99714 1/20 0.36
APOBEC3G Q9HC16 1/20 0.36
MEN1 O00255 2/20 0.33
CYP2C19 P33261 2/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
HSD11B1 P28845 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31317683 0.89 LMNA (0.35) ALDH1A1LMNAHPGDPOLBGAA
SCHEMBL2420027 0.85
SCHEMBL9957528 0.82 HTT (0.40) ALDH1A1KDM4EHPGDHTTALOX15
SCHEMBL9957046 0.78 POLB (0.38) ALDH1A1KDM4EPOLBKMT2AMEN1
SCHEMBL341318 0.77 SMN1; SMN2 (0.34) ALDH1A1KDM4ETSHRHSD17B10
SCHEMBL12156215 0.77 ALDH1A1 (0.46) ALDH1A1KDM4ELMNAHPGDPOLB
SCHEMBL9372265 0.76 HSD17B10 (0.40) GAATSHRHSD17B10
SCHEMBL15541721 0.75 SMN1; SMN2 (0.38) ALDH1A1HPGDPOLBGAATSHR
SCHEMBL342302 0.75 SMN1; SMN2 (0.38) ALDH1A1HPGDPOLBGAATSHR
SCHEMBL15561307 0.74 KDM4E (0.30) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260028442-A1 POLYMER COMPOSITION WHICH CAN BE CURED AT ROOM TEMPERATURE AND WHICH IS MADE OF POLYALDEHYDE AND 1,3 KETO ESTER SIKA TECHNOLOGY AG (CH) 2026-01-29 US disclosed
EP-4554995-A1 POLYMER COMPOSITION WHICH CAN BE CURED AT ROOM TEMPERATURE AND WHICH IS MADE OF POLYALDEHYDE AND 1,3 KETO ESTER Sika Technology AG (CH) 2025-05-21 EP disclosed
EP-4554996-A1 POLYMER COMPOSITION WHICH CAN BE CURED AT ROOM TEMPERATURE AND WHICH IS MADE OF POLYALDEHYDE AND POLYMALONATE Sika Technology AG (CH) 2025-05-21 EP disclosed
WO-2024012829-A1 POLYMER COMPOSITION WHICH CAN BE CURED AT ROOM TEMPERATURE AND WHICH IS MADE OF POLYALDEHYDE AND POLYMALONATE SIKA TECHNOLOGY AG (CH) 2024-01-18 WO disclosed
WO-2024012828-A1 POLYMER COMPOSITION WHICH CAN BE CURED AT ROOM TEMPERATURE AND WHICH IS MADE OF POLYALDEHYDE AND 1,3 KETO ESTER SIKA TECHNOLOGY AG (CH) 2024-01-18 WO disclosed
EP-2200970-B1 ALDEHYDES CONTAINING HYDROXYL GROUPS SIKA TECHNOLOGY AG (CH) 2016-01-06 EP disclosed
US-8389772-B2 Aldehydes containing hydroxl groups SIKA TECHNOLOGY AG (CH) 2013-03-05 US disclosed
US-20110195242-A1 ALDEHYDES CONTAINING HYDROXL GROUPS SIKA TECHNOLOGY AG (CH) 2011-08-11 US disclosed
EP-2200970-A1 ALDEHYDES CONTAINING HYDROXYL GROUPS Sika Technology AG (CH) 2010-06-30 EP disclosed
WO-2009027510-A1 ALDEHYDES CONTAINING HYDROXYL GROUPS SIKA TECHNOLOGY AG (CH) 2009-03-05 WO disclosed
EP-2030965-A1 Aldehydes containing hydroxyl groups Sika Technology AG (CH) 2009-03-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110195242-A1 ALDEHYDES CONTAINING HYDROXL GROUPS ALDH7A1, ALDH1A1, AOX1 ALDH1A1 2/4885KDM4E 559/4885LMNA 1740/4885
US-20260028442-A1 POLYMER COMPOSITION WHICH CAN BE CURED AT ROOM TEMPERATURE AND WHICH IS MADE OF POLYALDEHYDE AND 1,3 KETO ESTER VCAM1, ITGA1, ICAM1 ALDH1A1 30/4885KDM4E 184/4885LMNA 1575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.