SCHEMBL23212816

SCHEMBL23212816

Nc1cnn(C2CCc3cc(Cl)ccc32)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SRD5A1 P18405 4/20 0.39
▸ SRD5A2 P31213 2/20 0.39
▸ HTR2A P28223 1/20 0.38
▸ HTR2C P28335 1/20 0.38
▸ HTR2B P41595 1/20 0.38
▸ IDO1 P14902 1/20 0.37
▸ CTSD P07339 1/20 0.36
▸ MAP4K4 O95819 2/20 0.34
▸ PDE5A O76074 1/20 0.34
▸ CXCR3 P49682 1/20 0.34
▸ KDM5A P29375 1/20 0.33
▸ KDM4C Q9H3R0 1/20 0.33
▸ KDM5B Q9UGL1 1/20 0.33
▸ BACE1 P56817 1/20 0.33
▸ NTRK1 P04629 1/20 0.33
▸ TRPV1 Q8NER1 1/20 0.32
▸ FNTA P49354 1/20 0.32
▸ FNTB P49356 1/20 0.32
▸ TAAR1 Q96RJ0 1/20 0.32
▸ KIT P10721 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL23212926 0.99 SRD5A1 (0.38) SRD5A1SRD5A2HTR2AHTR2CHTR2B
SCHEMBL26969986 0.82 CHRNB2 (0.36) —
SCHEMBL23212917 0.80 CTSD (0.45) SRD5A1HTR2AHTR2CHTR2BCTSD
SCHEMBL22619811 0.80 HTR6 (0.41) IDO1CTSD
SCHEMBL30839410 0.80 HTR6 (0.41) IDO1CTSD
Hydrochloric Acid SCHEMBL22619864 0.78 IDO1 (0.41) IDO1CTSD
Hydrochloric Acid SCHEMBL31039804 0.78 IDO1 (0.41) IDO1CTSD
Hydrochloric Acid SCHEMBL22619807 0.78 IDO1 (0.41) IDO1CTSD
SCHEMBL23212828 0.78 SRD5A1 (0.38) SRD5A1SRD5A2CXCR3KDM5AKDM4C
SCHEMBL23212732 0.71 CHRNA7 (0.45) IDO1CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4041727-B1 ATF6 MODULATORS AND USES THEREOF ALTOS LABS INC (US) 2026-05-20 — — EP disclosed
CN-119823112-A ATF6 modulators and uses thereof 阿尔托斯实验室公司 2025-04-15 — — CN disclosed
CN-115135645-B ATF6 modulators and uses thereof 阿尔托斯实验室公司 2024-12-27 — — CN disclosed
US-20220389001-A1 ATF6 MODULATORS AND USES THEREOF ALTOS LABS, INC. 2022-12-08 — — US disclosed
US-20220389001-A1 ATF6 MODULATORS AND USES THEREOF ALTOS LABS, INC. 2022-12-08 — — US disclosed
CN-115135645-A ATF6 modulators and uses thereof 普拉西斯生物技术有限责任公司 2022-09-30 — — CN disclosed
EP-4041727-A1 ATF6 MODULATORS AND USES THEREOF Praxis Biotech LLC (US) 2022-08-17 — — EP disclosed
WO-2021069701-A1 ATF6 MODULATORS AND USES THEREOF BLACK BELT TX LTD (GB) 2021-04-15 — — WO disclosed
WO-2021069701-A1 ATF6 MODULATORS AND USES THEREOF BLACK BELT TX LTD (GB) 2021-04-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220389001-A1 ATF6 MODULATORS AND USES THEREOF ATF4, XBP1, ATF1 SRD5A1 3444/4885SRD5A2 3778/4885HTR2A 4598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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