Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.53 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.50 |
| ▸ | AGXT | P21549 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5927379 | 0.81 | KIF11 (0.63) | KIF11PTPN5MAOB | |
| SCHEMBL26821713 | 0.80 | KIF11 (0.73) | KIF11AGXTDHODHBACE1GLO1 | |
| SCHEMBL6215483 | 0.79 | GABRG2 (0.45) | PTPN5AGXTPTPN1 | |
| SCHEMBL97979 | 0.79 | CES2 (0.48) | PTPN1MGLL | |
| SCHEMBL97617 | 0.78 | MGLL (0.45) | PTPN5MGLL | |
| SCHEMBL16068255 | 0.77 | KIF11 (0.67) | KIF11AGXTDHODHPTPN1MAOB | |
| SCHEMBL4313331 | 0.76 | KIF11 (0.59) | KIF11AGXTDHODHBACE1GLO1 | |
| SCHEMBL11263406 | 0.76 | PTPN5 (0.36) | PTPN5MGLL | |
| SCHEMBL2321571 | 0.76 | PTPN5 (0.42) | PTPN5DHODH | |
| SCHEMBL2322395 | 0.76 | ESR1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |