Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902628 | 0.83 | ALDH1A1 (0.45) | MAOAHDAC8KMOHDAC4HDAC2 | |
| SCHEMBL2322395 | 0.83 | ESR1 (0.61) | XDHSLC22A12ALOX5 | |
| SCHEMBL6215483 | 0.83 | GABRG2 (0.45) | PTPN5GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL11263406 | 0.83 | PTPN5 (0.36) | MGLLPTPN5XDHSLC22A12MMP12 | |
| SCHEMBL2321571 | 0.83 | PTPN5 (0.42) | GRM5PTPN5XDHSLC22A12 | |
| SCHEMBL28833125 | 0.80 | CYP1A2 (0.50) | MGLLALDH1A1HTT | |
| SCHEMBL28886 | 0.79 | APP (0.35) | ALDH1A1 | |
| SCHEMBL2321711 | 0.78 | KIF11 (0.53) | MGLLPTPN5 | |
| SCHEMBL97063 | 0.77 | CYP1A2 (0.52) | MGLLALDH1A1FAAHHTT | |
| Hydrochloric Acid SCHEMBL9124177 | 0.76 | CYP3A4 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE48335-E1 | Polymyxin derivatives as antimicrobial compounds | MONASH UNIVERSITY (AU) | 2020-12-01 | — | — | US | claimed |
| CN-109796418-A | Phenylalanine derivative and the preparation method and application thereof containing 4- phenyl -1,2,3- triazole | 山东大学 | 2019-05-24 | — | — | CN | claimed |
| US-20170137469-A1 | POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS | MONASH UNIVERSITY (AU) | 2017-05-18 | — | — | US | claimed |
| EP-3126376-A1 | POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS | Monash University (AU) | 2017-02-08 | — | — | EP | claimed |
| WO-2015149131-A1 | POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS | MONASH UNIVERSITY (AU) | 2015-10-08 | — | — | WO | claimed |
| US-20230099775-A1 | CURABLE COMPOSITION, CURED PRODUCT, CURED FILM, DISPLAY PANEL, AND METHOD FOR PRODUCING CURED FILM | TOKYO OHKA KOGYO CO., LTD. (JP) | 2023-03-30 | — | — | US | disclosed |
| CN-115703939-A | Curable composition, cured product, cured film, display panel, and method for producing cured film | 东京应化工业株式会社 | 2023-02-17 | — | — | CN | disclosed |
| CN-114545731-A | Photosensitive composition for forming optical member, cured product, microlens, method for producing microlens pattern, and microlens | 东京应化工业株式会社 | 2022-05-27 | — | — | CN | disclosed |
| CN-114502613-A | Curable composition, cured product, and method for forming cured product | 东京应化工业株式会社 | 2022-05-13 | — | — | CN | disclosed |
| CN-109796418-B | Phenylalanine derivative containing 4-phenyl-1, 2, 3-triazole and preparation method and application thereof | 山东大学 | 2022-03-25 | — | — | CN | disclosed |
| US-20210395209-A1 | NUCLEATING AGENT, SYNTHETIC-RESIN COMPOSITION CONTAINING SAME, AND MOLDED OBJECT THEREOF | ADEKA CORPORATION (JP) | 2021-12-23 | — | — | US | disclosed |
| EP-3858909-A1 | NUCLEATING AGENT, SYNTHETIC-RESIN COMPOSITION CONTAINING SAME, AND MOLDED OBJECT THEREOF | ADEKA CORPORATION (JP) | 2021-08-04 | — | — | EP | disclosed |
| WO-2006035954-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-04-06 | — | — | WO | disclosed |
| US-20050282730-A1 | Thrombopoetin receptor activator and process for producing the same | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2005-12-22 | — | — | US | disclosed |
| WO-2005090357-A1 | TRICYCLIC BENZOPYRAN COMPOUND AS ANTI-ARRHYTHMIC AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2005-09-29 | — | — | WO | disclosed |
| WO-2005080368-A2 | BENZOPYRAN COMPOUND USEFUL FOR THE TREATMENT OF ARRHYTMIA | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2005-09-01 | — | — | WO | disclosed |
| EP-1552828-A1 | THROMBOPOETIN RECEPTOR ACTIVATOR AND PROCESS FOR PRODUCING THE SAME | Nissan Chemical Industries, Ltd. (JP) | 2005-07-13 | — | — | EP | disclosed |
| EP-0929217-B1 | SORDARIN DERIVATIVES | MERCK & CO INC (US) | 2004-03-03 | — | — | EP | disclosed |
| EP-1007032-B1 | 4-CYANO-4-DEFORMYLSORDARICIN DERIVATIVES | MERCK & CO INC (US) | 2003-04-23 | — | — | EP | disclosed |
| EP-1233014-A1 | ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME | NOF CORPORATION (JP) | 2002-08-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210395209-A1 | NUCLEATING AGENT, SYNTHETIC-RESIN COMPOSITION CONTAINING SAME, AND MOLDED OBJECT THEREOF | NOC2L, RIF1, NAP1L1 | MGLL 4448/4885MAOA 4128/4885HDAC8 1857/4885 |
| US-20050282730-A1 | Thrombopoetin receptor activator and process for producing the same | PDGFRA, PTAFR, TBXA2R | MGLL 3781/4885MAOA 2558/4885HDAC8 2725/4885 |
| US-20170137469-A1 | POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS | VIP, PEPD, NRDC | MGLL 1234/4885MAOA 4503/4885HDAC8 2914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.