Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.55 |
| ▸ | CSF1R | P07333 | 1/20 | 0.55 |
| ▸ | RET | P07949 | 1/20 | 0.55 |
| ▸ | MET | P08581 | 1/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.55 |
| ▸ | FLT3 | P36888 | 1/20 | 0.55 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.55 |
| ▸ | CDK8 | P49336 | 1/20 | 0.55 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.55 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.55 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6673320 | 0.80 | AURKA (0.55) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL2322295 | 0.79 | KDM1A (0.45) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL2322134 | 0.78 | AURKA (0.50) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL2321986 | 0.77 | KIF11 (0.50) | CYP3A4MEN1LMNAKMT2AMAPT | |
| SCHEMBL28103663 | 0.77 | TDP1 (0.59) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL26846320 | 0.76 | AURKA (0.58) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL17051522 | 0.75 | CCR1 (0.65) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL2477927 | 0.75 | CCR1 (0.71) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL428216 | 0.74 | MEN1 (0.48) | CYP3A4MEN1LMNAKMT2AMAPT | |
| SCHEMBL10000250 | 0.73 | CCR1 (0.54) | AURKAABL1NTRK1LCKCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |