Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12855304 | 0.81 | ALDH1A1 (0.57) | KDM1ACCR1CCR5CCR8HDAC6 | |
| SCHEMBL27896907 | 0.81 | LDHA (0.52) | GRM5 | |
| SCHEMBL27432976 | 0.80 | KDM1A (0.47) | KDM1ACCR1CCR5CCR8HDAC6 | |
| SCHEMBL2322131 | 0.79 | AURKA (0.55) | KDM1ACCR1CCR5CCR8HDAC6 | |
| SCHEMBL17051522 | 0.78 | CCR1 (0.65) | KDM1ACCR1CCR5CCR8HDAC6 | |
| SCHEMBL2477927 | 0.78 | CCR1 (0.71) | KDM1ACCR1CCR5CCR8HDAC6 | |
| SCHEMBL10000248 | 0.76 | CCR1 (0.68) | KDM1ACCR1CCR5CCR8HDAC6 | |
| SCHEMBL10000250 | 0.76 | CCR1 (0.54) | KDM1ACCR1CCR5CCR8HDAC6 | |
| SCHEMBL17051514 | 0.75 | CCR1 (0.75) | KDM1ACCR1CCR5CCR8HDAC6 | |
| SCHEMBL91847 | 0.75 | ALDH1A1 (0.55) | KDM1ACCR1CCR5CCR8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |