SCHEMBL2327870

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2326219	0.81	MAPT (0.39)	HTR6HTTKDM4EMAPTGAA
	SCHEMBL2331812	0.79	HRH4 (0.38)	HPGD
	SCHEMBL12444837	0.78	LMNA (0.45)	HPGDLMNAMEN1KMT2AHTR6
	SCHEMBL3620002	0.74	KDM4E (0.46)	KMT2AHTTKDM4EMAPTGAA
	SCHEMBL14717300	0.74	HPGD (0.50)	HPGDLMNAMEN1KMT2AHTT
	SCHEMBL2335075	0.74	HPGD (0.41)	HPGDLMNAMEN1KMT2AHTR6
	SCHEMBL10514464	0.73	ALDH1A1 (0.47)	ALDH1A1
	SCHEMBL2325963	0.72	MAPT (0.55)	HPGDLMNAHTR6HTTKDM4E
	SCHEMBL12444816	0.72	DRD2 (0.36)	HTTKDM4EMAPTGAAMAPK1
	SCHEMBL2361358	0.71	HPGD (0.39)	HPGDLMNAMEN1KMT2AHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.