SCHEMBL2326219

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2333109	0.83	MAPT (0.39)	MAPTKDM4EGAAMAPK1HTT
	SCHEMBL2327474	0.81	HTR6 (0.36)	HTTDRD2HTR2ADRD3HTR1A
	SCHEMBL2327870	0.81	HPGD (0.43)	MAPTKDM4EGAAMAPK1HTT
	SCHEMBL2329668	0.79	ALOX15 (0.37)	HTR3A
	SCHEMBL12444827	0.78	TNKS (0.34)	DRD2HTR2ADRD3HTR1AHTR1D
	SCHEMBL2328357	0.76	MAPT (0.43)	MAPTKDM4EGAAMAPK1HTT
	SCHEMBL3620002	0.74	KDM4E (0.46)	MAPTKDM4EGAAMAPK1HTT
	SCHEMBL2328336	0.74	DRD2 (0.47)	MAPTKDM4EGAAMAPK1HTT
	SCHEMBL10514464	0.73	ALDH1A1 (0.47)	HTR3A
	SCHEMBL12444816	0.72	DRD2 (0.36)	MAPTKDM4EGAAMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.