SCHEMBL23296293

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22562362	0.89	ADORA1 (0.44)	ADORA2AADORA1NCOA1NCOA3KDM4E
	SCHEMBL23296337	0.88	TGFBR1 (0.39)	IRAK4TGFBR1CCR1CCR8CYP2A6
	SCHEMBL22562197	0.88	TGFBR1 (0.37)	IRAK4TGFBR1CCR1CCR8THRB
	SCHEMBL23296383	0.87	TGFBR1 (0.40)	IRAK4TGFBR1ADORA2AADORA1NCOA1
	SCHEMBL22562204	0.86	ADORA1 (0.42)	ADORA2AADORA1NCOA1NCOA3KDM4E
	SCHEMBL22562387	0.85	TGFBR1 (0.39)	TGFBR1ADORA2AADORA1HIF1A
	SCHEMBL22562198	0.84	TGFBR1 (0.37)	IRAK4TGFBR1KDM4EHPGDLMNA
	SCHEMBL23296385	0.83	LMNA (0.36)	ADORA2AADORA1THRBNCOA1NCOA3
	SCHEMBL23296381	0.83	GRM5 (0.42)	KDM4EHPGDLMNAPOLBHTT
	SCHEMBL31272987	0.83	GRM5 (0.42)	KDM4EHPGDLMNAPOLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.