Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARD | Q03181 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27167469 | 0.98 | CES2 (0.52) | CES2CES1GPR84PPARGPPARD | |
| Sulfuric Acid SCHEMBL28748101 | 0.90 | CES2 (0.45) | CES2CES1GPR84PPARGPPARD | |
| Hydrochloric Acid SCHEMBL29941015 | 0.89 | FABP3 (0.59) | PPARGPPARDPPARAPTPN1TDP1 | |
| Hydrochloric Acid SCHEMBL28331063 | 0.83 | CES2 (0.50) | CES2CES1GPR84PPARGPPARD | |
| Hydrochloric Acid SCHEMBL3148020 | 0.83 | CES2 (0.50) | CES2CES1GPR84PPARGPPARD | |
| Hydrochloric Acid SCHEMBL3842195 | 0.82 | CES2 (0.54) | CES2CES1GPR84PPARGPPARD | |
| Hydrochloric Acid SCHEMBL1975595 | 0.82 | CES2 (0.54) | CES2CES1GPR84PPARGPPARD | |
| Hydrochloric Acid SCHEMBL8810257 | 0.82 | CES2 (0.54) | CES2CES1GPR84PPARGPPARD | |
| Hydrochloric Acid SCHEMBL564166 | 0.82 | CES2 (0.54) | CES2CES1GPR84PPARGPPARD | |
| Hydrochloric Acid SCHEMBL994706 | 0.82 | CES2 (0.54) | CES2CES1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122055434-A | Short chain free bar compositions comprising C18:3 soaps | 联合利华知识产权控股有限公司 | 2026-05-15 | — | — | CN | disclosed |
| US-20260132356-A1 | MILD WASH COMPOSITION WITH BIODEGRADABLE THICKENER AND ENHANCED MICROBIOTA IMPACT | CONOPCO, INC., D/B/A UNILEVER (US) | 2026-05-14 | — | — | US | disclosed |
| US-12622861-B2 | Stable wash composition | CONOPCO, INC. (US) | 2026-05-12 | — | — | US | disclosed |
| EP-4734945-A1 | WASH COMPOSITION WITH ANIONIC SULFATE AND SULTAINE NOT RELIANT ON PALM KERNEL OIL | Unilever IP Holdings B.V. (NL) | 2026-05-06 | — | — | EP | disclosed |
| EP-4171489-B1 | SANITIZING COMPOSITION | UNILEVER IP HOLDINGS B V (NL) | 2026-03-25 | — | — | EP | disclosed |
| US-20260076893-A1 | SELF-FOAMING CLEANSING COMPOSITION | CONOPCO, INC., D/B/A UNILEVER (US) | 2026-03-19 | — | — | US | disclosed |
| EP-4593790-B1 | MILD WASH COMPOSITION WITH BIODEGRADABLE THICKENER AND ENHANCED MICROBIOTA IMPACT | UNILEVER IP HOLDINGS B V (NL) | 2026-03-18 | — | — | EP | disclosed |
| EP-4704789-A1 | LAMELLAR WASH COMPOSITION NOT RELIANT ON PALM KERNEL OIL DERIVED STRUCTURANT | Unilever IP Holdings B.V. (NL) | 2026-03-11 | — | — | EP | disclosed |
| EP-4704788-A1 | MILD LAMELLAR WASH COMPOSITION HAVING REDUCED ISETHIONATE AND PALM KERNEL OIL DERIVED STRUCTURANT | Unilever IP Holdings B.V. (NL) | 2026-03-11 | — | — | EP | disclosed |
| EP-4704787-A1 | LAMELLAR WASH COMPOSITION WITH REDUCED PALM KERNEL OIL RELIANCE | Unilever IP Holdings B.V. (NL) | 2026-03-11 | — | — | EP | disclosed |
| US-20210401701-A1 | ANTIDANDRUFF COMPOSITION | CONOPCO, INC., D/B/A UNILEVER (US) | 2021-12-30 | — | — | US | disclosed |
| WO-2021224114-A1 | ANTIBACTERIAL COMPOSITION | UNILEVER IP HOLDINGS B.V. (NL) | 2021-11-11 | — | — | WO | disclosed |
| WO-2021197906-A1 | CLEANSING COMPOSITION | UNILEVER IP HOLDINGS B.V. (NL) | 2021-10-07 | — | — | WO | disclosed |
| US-20210299013-A1 | Compositions Comprising Naturally Derived Preservatives | CONOPCO, INC., D/B/A UNILEVER (US) | 2021-09-30 | — | — | US | disclosed |
| WO-2021191185-A1 | COMPOSITIONS COMPRISING NATURALLY DERIVED PRESERVATIVES | UNILEVER IP HOLDINGS B.V. (NL) | 2021-09-30 | — | — | WO | disclosed |
| WO-2021148428-A1 | ISOTROPIC CONCENTRATE AND WASH COMPOSITIONS | UNILEVER IP HOLDINGS B.V. (NL) | 2021-07-29 | — | — | WO | disclosed |
| WO-2021148427-A1 | HYDRATABLE CONCENTRATED SURFACTANT COMPOSITION | UNILEVER IP HOLDINGS B.V. (NL) | 2021-07-29 | — | — | WO | disclosed |
| US-20210220243-A1 | Hydratable Concentrated Surfactant Composition | CONOPCO, INC., D/B/A UNILEVER (US) | 2021-07-22 | — | — | US | disclosed |
| WO-2021104844-A1 | CLEANSING COMPOSITION | UNILEVER IP HOLDINGS B.V. (NL) | 2021-06-03 | — | — | WO | disclosed |
| WO-2021084007-A1 | FOAM PRECURSOR LIQUID AND FOAM CLEANSING COMPOSITION | UNILEVER IP HOLDINGS B.V. (NL) | 2021-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12622861-B2 | Stable wash composition | ALG1, IL4, CUTA | CES2 500/4885CES1 786/4885GPR84 499/4885 |
| US-20260132356-A1 | MILD WASH COMPOSITION WITH BIODEGRADABLE THICKENER AND ENHANCED MICROBIOTA IMPACT | WASHC4, MUC1, WASHC5 | CES2 544/4885CES1 617/4885GPR84 822/4885 |
| US-20260076893-A1 | SELF-FOAMING CLEANSING COMPOSITION | FASN, LSS, LIPA | CES2 2264/4885CES1 990/4885GPR84 3218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.