Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARD | Q03181 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28331063 | 1.00 | CES2 (0.50) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL17077912 | 0.98 | CES2 (0.52) | CES2CES1GPR84PPARGPPARD | |
| Sulfuric Acid SCHEMBL27481563 | 0.90 | CES2 (0.45) | CES2CES1GPR84PPARGPPARD | |
| Sulfuric Acid SCHEMBL27481562 | 0.88 | CES2 (0.48) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL28876841 | 0.87 | FABP3 (0.61) | PPARGPPARDPPARAPTPN1TDP1 | |
| Bromide SCHEMBL2810645 | 0.85 | FABP3 (0.59) | PPARGPPARDPPARAPTPN1TDP1 | |
| Bromide SCHEMBL27788998 | 0.85 | FABP3 (0.59) | PPARGPPARDPPARAPTPN1TDP1 | |
| Hydrochloric Acid SCHEMBL28345403 | 0.85 | CES2 (0.48) | CES2CES1GPR84PPARGPPARD | |
| Hydrochloric Acid SCHEMBL23301618 | 0.83 | CES2 (0.50) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL29391004 | 0.83 | CES2 (0.50) | CES2CES1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118904086-A | Preparation and application of reverse osmosis membrane cleaning agent | 福州盈科水处理工程有限公司 | 2024-11-08 | — | — | CN | claimed |
| CN-118904086-A | Preparation and application of reverse osmosis membrane cleaning agent | 福州盈科水处理工程有限公司 | 2024-11-08 | — | — | CN | disclosed |
| US-12035861-B2 | Fibrous structures comprising particles and methods for making same | THE PROCTER & GAMBLE COMPANY (US) | 2024-07-16 | — | — | US | disclosed |
| US-20200275818-A1 | Fibrous Structures Comprising Particles and Methods for Making Same | THE PROCTER & GAMBLE COMPANY | 2020-09-03 | — | — | US | disclosed |
| US-9421153-B2 | Detergent product and method for making same | THE PROCTER & GAMBLE COMPANY (US) | 2016-08-23 | — | — | US | disclosed |
| US-20140287973-A1 | DETERGENT PRODUCT AND METHOD FOR MAKING SAME | PROCTER & GAMBLE (US) | 2014-09-25 | — | — | US | disclosed |
| US-20100286101-A1 | PHARMACEUTICAL COMPOSITION INCLUDING A CORTICOSTEROID AND A VITAMIN D ANALOG HAVING IMPROVED STABILITY | CARBOL JASON | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12035861-B2 | Fibrous structures comprising particles and methods for making same | FGB, CD68, SDCBP | CES2 2307/4885CES1 2200/4885GPR84 4350/4885 |
| US-20200275818-A1 | Fibrous Structures Comprising Particles and Methods for Making Same | FGB, CD68, SDCBP | CES2 2307/4885CES1 2200/4885GPR84 4350/4885 |
| US-20100286101-A1 | PHARMACEUTICAL COMPOSITION INCLUDING A CORTICOSTEROID AND A VITAMIN D ANALOG HAVING IMPROVED STABILITY | CYP24A1, CYP2R1, VDR | CES2 3032/4885CES1 285/4885GPR84 1249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.