SCHEMBL233151

SCHEMBL233151

COc1ccc(N2CCNCC2)c(OC)c1

nearest known ligand 0.77

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR3A P46098 5/20 0.71
HTR3E A5X5Y0 4/20 0.71
HTR3B O95264 4/20 0.71
HTR3D Q70Z44 4/20 0.71
HTR3C Q8WXA8 4/20 0.71
ADRB1 P08588 4/20 0.63
SIGMAR1 Q99720 2/20 0.63
DRD2 P14416 1/20 0.63
CYP2C19 P33261 1/20 0.63
DRD3 P35462 1/20 0.63
HTR6 P50406 1/20 0.63
HTR1A P08908 3/20 0.61
LMNA P02545 1/20 0.61
MAPT P10636 1/20 0.61
NCF1 P14598 1/20 0.56
HTR1D P28221 1/20 0.55
HTR1B P28222 1/20 0.55
HTR7 P34969 2/20 0.54
KMT2A Q03164 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30747759 1.00 HTR3A (0.71) HTR3AHTR3EHTR3BHTR3DHTR3C
Hydrochloric Acid SCHEMBL7711668 0.98 HTR3A (0.69) HTR3AHTR3EHTR3BHTR3DHTR3C
Hydrochloric Acid SCHEMBL4905371 0.98 HTR3A (0.69) HTR3AHTR3EHTR3BHTR3DHTR3C
SCHEMBL12932476 0.94 HTR3A (0.64) HTR3AHTR3EHTR3BHTR3DHTR3C
SCHEMBL6710534 0.93 HTR3A (0.62) HTR3AHTR3EHTR3BHTR3DHTR3C
Hydrochloric Acid SCHEMBL1062874 0.93 HTR3A (0.62) HTR3AHTR3EHTR3BHTR3DHTR3C
SCHEMBL2349863 0.87 HTR3A (0.69) HTR3AHTR3EHTR3BHTR3DHTR3C
Hydrochloric Acid SCHEMBL7708526 0.85 HTR3A (0.68) HTR3AHTR3EHTR3BHTR3DHTR3C
SCHEMBL6928763 0.85 HTR3A (0.54) HTR3AHTR3EHTR3BHTR3DHTR3C
SCHEMBL5566877 0.84 ALDH1A1 (0.61) HTR3AHTR3EHTR3BHTR3DHTR3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 465 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106074204-B A kind of application of genistein derivative in whitening field 山东理工大学 2018-10-23 CN claimed
CN-106260498-A The manufacture method of a kind of Semen Pisi sativi protein peptide and application 山东理工大学 2017-01-04 CN claimed
CN-106281935-A A kind of method promoting neutral protease activity and the application in beer clarification thereof 山东理工大学 2017-01-04 CN claimed
CN-106065389-A A kind of method promoting papain activity and the application in beer clarification thereof 山东理工大学 2016-11-02 CN claimed
CN-106011121-A Method for promoting neutral protease activity and use thereof 烟台双塔食品股份有限公司 2016-10-12 CN claimed
CN-106011211-A Method for preparing pea protein polypeptide powder 烟台双塔食品股份有限公司 2016-10-12 CN claimed
EP-1831206-B1 N-SUBSTITUTED BENZIMIDAZOLYL C-KIT INHIBITORS AND COMBINATORIAL BENZIMIDAZOLE LIBRARY OSI PHARM INC (US) 2011-08-24 EP claimed
JP-2008521903-A 2008-06-26 JP claimed
EP-1831206-A2 N-SUBSTITUTED BENZIMIDAZOLYL C-KIT INHIBITORS AND COMBINATORIAL BENZIMIDAZOLE LIBRARY OSI Pharmaceuticals, Inc. (US) 2007-09-12 EP claimed
WO-2006060381-A2 N-SUBSTITUTED BENZIMIDAZOLYL C-KIT INHIBITORS AND COMBINATORIAL BENZIMIDAZOLE LIBRARY OSI PHARMACEUTICALS, INC. (US) 2006-06-08 WO claimed
US-20060116402-A1 N-substituted benzimidazolyl c-Kit inhibitors and combinatorial benzimidazole library OSI PHARMACEUTICALS, INC. 2006-06-01 US claimed
US-20260092134-A1 Bioreducible Poly (Beta-Amino Ester)s For siRNA Delivery UNIV JOHNS HOPKINS (US) 2026-04-02 US disclosed
US-12527746-B2 Peptide/particle delivery systems THE JOHNS HOPKINS UNIVERSITY (US) 2026-01-20 US disclosed
US-12458700-B2 Amine-containing transfection reagents and methods for making and using same Life Technologies Corporation (US) 2025-11-04 US disclosed
US-12371522-B2 Bioreducible poly (beta-amino ester)s for siRNA delivery THE JOHNS HOPKINS UNIVERSITY (US) 2025-07-29 US disclosed
EP-0711757-A1 3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy -pyridine, pyrimidine and benzene derivatives as alpha1-adrenoceptor antagonists F. Hoffmann-La Roche AG (CH) 1996-05-15 EP disclosed
EP-0322643-B1 MEDICINES CONTAINING AS A MIXTURE INTERFERON AND 1-DESOXY-PIPERIDINOSES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE BAYER AG (DE) 1991-07-24 EP disclosed
US-4940705-A VIRICIDES BAYER AKTIENGESELLSCHAFT (DE) 1990-07-10 US disclosed
EP-0322643-A1 Medicines containing as a mixture interferon and 1-desoxy-piperidinoses, process for their manufacture and their use BAYER AG (DE) 1989-07-05 EP disclosed
EP-0313974-A1 N-substituted derivatives of 1-desoxynojirimycine and 1-desoxymannonojirimycine, process for their preparation and their use as pharmaceuticals BAYER AG (DE) 1989-05-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527746-B2 Peptide/particle delivery systems VEGFA, IGF2BP2, MSTN HTR3A 2147/4885HTR3E 1396/4885HTR3B 1999/4885
US-12458700-B2 Amine-containing transfection reagents and methods for making and using same SNRPA, NUDT21, SOAT2 HTR3A 2204/4885HTR3E 2058/4885HTR3B 1563/4885
US-12371522-B2 Bioreducible poly (beta-amino ester)s for siRNA delivery AARS1, SLC43A1, PHAX HTR3A 4002/4885HTR3E 3145/4885HTR3B 3494/4885
US-20060116402-A1 N-substituted benzimidazolyl c-Kit inhibitors and combinatorial benzimidazole library KIT, CHUK, TNNI3K HTR3A 2646/4885HTR3E 3320/4885HTR3B 2852/4885
US-20260092134-A1 Bioreducible Poly (Beta-Amino Ester)s For siRNA Delivery SLC43A1, SLC7A5, SLC7A1 HTR3A 4257/4885HTR3E 3569/4885HTR3B 4492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.