Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.40 |
| ▸ | MLYCD | O95822 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11655940 | 0.80 | HDAC6 (0.47) | HDAC6HDAC8HDAC1PTPN1MLYCD | |
| Hydrochloric Acid SCHEMBL11651072 | 0.79 | HDAC6 (0.46) | HDAC6HDAC8HDAC1PTPN1MLYCD | |
| SCHEMBL12632249 | 0.79 | LSS (0.49) | HDAC6HDAC1PTPN1HRH3LMNA | |
| SCHEMBL11706284 | 0.76 | ACHE (0.47) | HDAC6HDAC8HDAC1PTPN1SMN1; SMN2 | |
| SCHEMBL8792653 | 0.75 | PTGS1 (0.50) | MEN1KMT2ALMNASMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL2457698 | 0.75 | ACHE (0.46) | PTPN1SMN1; SMN2PYCR1ALDH1A1 | |
| SCHEMBL10031827 | 0.73 | PGR (0.47) | HDAC1MLYCDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL13153417 | 0.73 | RIPK1 (0.44) | PYCR1ALDH1A1 | |
| SCHEMBL25530561 | 0.73 | TSHR (0.46) | HDAC6HDAC8LMNAHDAC11 | |
| SCHEMBL1628100 | 0.72 | ALDH1A1 (0.59) | LMNASMN1; SMN2HPGDALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210128740-A1 | HDAC INHIBITORS-BASED ANTIBODY DRUG CONJUGATES (ADCs) AND USE IN THERAPY | ALFASIGMA S.P.A. (IT) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210128740-A1 | HDAC INHIBITORS-BASED ANTIBODY DRUG CONJUGATES (ADCs) AND USE IN THERAPY | ERBB3, HDAC6, ERBB2 | HDAC6 2/4885HDAC8 6/4885HDAC1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.