Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | ELANE | P08246 | 17/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23337944 | 0.84 | ALDH1A1 (0.72) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| SCHEMBL11526487 | 0.83 | LMNA (0.71) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| SCHEMBL23339689 | 0.83 | LMNA (0.71) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| SCHEMBL21510456 | 0.78 | TSHR (0.45) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| Hydrochloric Acid SCHEMBL11638787 | 0.75 | ADRB2 (0.59) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| SCHEMBL11264848 | 0.74 | ALDH1A1 (0.71) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| SCHEMBL11053289 | 0.74 | HIF1A (0.58) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| Hydrochloric Acid SCHEMBL10914813 | 0.73 | ADRB2 (0.60) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| SCHEMBL11284714 | 0.73 | LMNA (0.48) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| SCHEMBL2356556 | 0.72 | ALDH1A1 (0.57) | ALDH1A1LMNACYP3A4HIF1AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021087359-A1 | PRODRUG COMPOSITIONS AND METHODS OF TREATMENT | AQUESTIVE THERAPEUTICS, INC. (US) | 2021-05-06 | — | — | WO | disclosed |