SCHEMBL23319142

SCHEMBL23319142

CCOC(=O)C1(NC(=O)CC(C)(C)NC(=O)OC(C)(C)C)CC1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
HTT P42858 1/20 0.32
APLNR P35414 1/20 0.31
GHSR Q92847 1/20 0.31
PTPRB P23467 1/20 0.31
CTSL P07711 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL583634 0.83 KMT2A (0.38) MEN1ALDH1A1TSHRKMT2ACYP1A2
SCHEMBL1351011 0.77 LATS1 (0.37) MEN1ALDH1A1TSHRKMT2ACYP1A2
SCHEMBL19706901 0.76 GHSR (0.40) MEN1ALDH1A1TSHRKMT2ACYP1A2
SCHEMBL28302110 0.76 KMT2A (0.39) MEN1ALDH1A1TSHRKMT2ACYP1A2
SCHEMBL2781817 0.74 OPRM1 (0.42) MEN1ALDH1A1TSHRKMT2ACYP1A2
SCHEMBL2746842 0.74 GHSR (0.36) MEN1ALDH1A1TSHRKMT2ACYP1A2
SCHEMBL15903847 0.74 CYP1A2 (0.46) MEN1ALDH1A1TSHRKMT2ACYP1A2
SCHEMBL13525930 0.72 KMT2A (0.38) MEN1ALDH1A1TSHRKMT2ACYP1A2
SCHEMBL10040060 0.72 KMT2A (0.38) MEN1ALDH1A1TSHRKMT2ACYP1A2
SCHEMBL298008 0.72 KMT2A (0.38) MEN1ALDH1A1TSHRKMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240209020-A1 REACTION AGENT FOR AMIDE REACTION AND METHOD FOR PRODUCING AMIDE COMPOUND USING SAME CHUBU UNIVERSITY EDUCATIONAL FOUNDATION (JP) 2024-06-27 US disclosed
WO-2021085635-A1 REACTION AGENT FOR AMIDE REACTION AND METHOD FOR PRODUCING AMIDE COMPOUND USING SAME 学校法人中部大学 2021-05-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240209020-A1 REACTION AGENT FOR AMIDE REACTION AND METHOD FOR PRODUCING AMIDE COMPOUND USING SAME NAAA, FAAH, FAAH2 MEN1 1214/4885ALDH1A1 386/4885TSHR 1978/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.