Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL23320496 | 0.83 | NAMPT (0.55) | ROCK2ROCK1NAMPTHTT | |
| SCHEMBL23320574 | 0.72 | ROCK2 (0.50) | ALDH1A1TSHRHSD17B10ROCK2ROCK1 | |
| Formamide SCHEMBL23320541 | 0.72 | ALDH1A1 (0.48) | ALDH1A1TSHRHSD17B10ROCK2ROCK1 | |
| SCHEMBL11615932 | 0.71 | HSD17B10 (0.79) | ALDH1A1TSHRHSD17B10ROCK2ROCK1 | |
| SCHEMBL4531077 | 0.67 | HSD17B10 (0.70) | ALDH1A1TSHRHSD17B10ROCK2ROCK1 | |
| SCHEMBL4519247 | 0.67 | HSD17B10 (0.70) | ALDH1A1TSHRHSD17B10ROCK2ROCK1 | |
| Formamide SCHEMBL23320449 | 0.67 | ALDH1A1 (0.43) | ALDH1A1TSHRHSD17B10ROCK2ROCK1 | |
| Formamide SCHEMBL23320546 | 0.66 | MAPK14 (0.46) | ALDH1A1TSHRHSD17B10MAPK14GAA | |
| SCHEMBL23320366 | 0.65 | NAMPT (0.66) | ALDH1A1TSHRHSD17B10ROCK2ROCK1 | |
| SCHEMBL23320404 | 0.63 | NAMPT (0.64) | ROCK2ROCK1NAMPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |