Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL23320515 | 0.87 | NAMPT (0.52) | HTT | |
| Formamide SCHEMBL23320541 | 0.78 | ALDH1A1 (0.48) | KMT2ATSHR | |
| SCHEMBL20380104 | 0.70 | L3MBTL1 (1.00) | L3MBTL1KMT2ASMN1; SMN2ALOX15NPC1 | |
| SCHEMBL11618998 | 0.70 | RAB9A (1.00) | L3MBTL1KMT2ASMN1; SMN2ALOX15NPC1 | |
| SCHEMBL8936567 | 0.67 | TACR1 (0.74) | L3MBTL1KMT2ASMN1; SMN2ALOX15NPC1 | |
| Formamide SCHEMBL23320507 | 0.67 | ALDH1A1 (0.62) | L3MBTL1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL17117408 | 0.66 | RORC (0.61) | KMT2ANPC1RAB9AMAPTCA12 | |
| SCHEMBL30818065 | 0.66 | NPC1 (0.78) | L3MBTL1KMT2ASMN1; SMN2ALOX15NPC1 | |
| SCHEMBL20379469 | 0.66 | NPC1 (0.78) | L3MBTL1KMT2ASMN1; SMN2ALOX15NPC1 | |
| SCHEMBL18317596 | 0.66 | RAB9A (0.80) | L3MBTL1KMT2ASMN1; SMN2ALOX15NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |