Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 5/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | MST1R | Q04912 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27157147 | 0.81 | FGFR1 (0.43) | METFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL23320538 | 0.79 | FGFR1 (0.41) | METFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL31344824 | 0.70 | NPC1 (0.61) | METPIM1PIM2KDM4ENPC1 | |
| SCHEMBL23320510 | 0.68 | NAMPT (0.71) | NPC1ALDH1A1RAB9A | |
| SCHEMBL23320473 | 0.66 | CYP19A1 (0.41) | ALDH1A1HPGD | |
| SCHEMBL30943251 | 0.65 | RAB9A (0.63) | METNPC1ALDH1A1RAB9A | |
| SCHEMBL29000685 | 0.64 | MET (0.64) | METKDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL23320490 | 0.63 | ALOX5 (0.38) | NPC1ALDH1A1RAB9A | |
| SCHEMBL17544220 | 0.63 | ESR1 (0.61) | METPIM1PIM2KDM4ENPC1 | |
| SCHEMBL23320378 | 0.62 | ADORA3 (0.37) | MKNK1KDRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |