Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NNMT | P40261 | 2/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4948493 | 0.98 | KDM4E (0.60) | KDM4EALDH1A1HSD17B10LMNAMAPT | |
| Potassium SCHEMBL29692209 | 0.96 | KDM4E (0.58) | KDM4EALDH1A1HSD17B10LMNAMAPT | |
| Hydrochloric Acid SCHEMBL23320590 | 0.96 | ALDH1A1 (0.58) | KDM4EALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL16400491 | 0.82 | KDM4E (0.60) | KDM4EALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL4596357 | 0.81 | LMNA (0.59) | KDM4EALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL28476110 | 0.81 | KDM4E (0.58) | KDM4EALDH1A1HSD17B10MAPTRAB9A | |
| SCHEMBL27816536 | 0.78 | PREP (0.42) | KDM4EALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL22557537 | 0.77 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL2414089 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10MAPTRAB9A | |
| SCHEMBL27379515 | 0.77 | PTK2 (0.49) | KDM4EALDH1A1HSD17B10RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11999724-B2 | Method for producing diarylpyridine derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2024-06-04 | — | — | US | disclosed |
| EP-3819296-B1 | METHOD FOR PRODUCING DIARYLPYRIDINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2022-06-29 | — | — | EP | disclosed |
| US-20210188823-A1 | Method for Producing Diarylpyridine Derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-06-24 | — | — | US | disclosed |
| EP-3819296-A1 | METHOD FOR PRODUCING DIARYLPYRIDINE DERIVATIVES | Daiichi Sankyo Company, Limited (JP) | 2021-05-12 | — | — | EP | disclosed |
| CN-112368271-A | Process for producing diarylpyridine derivative | 第一三共株式会社 | 2021-02-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188823-A1 | Method for Producing Diarylpyridine Derivatives | QDPR, DPYD, DHPS | KDM4E 1970/4885ALDH1A1 1570/4885HSD17B10 2311/4885 |
| US-11999724-B2 | Method for producing diarylpyridine derivatives | QDPR, DPYD, DHPS | KDM4E 1970/4885ALDH1A1 1570/4885HSD17B10 2311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.