Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | LIPE | Q05469 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL903584 | 0.84 | RAB9A (0.56) | LMNAKDM4ELIPERAB9ANPC1 | |
| SCHEMBL4948493 | 0.83 | KDM4E (0.60) | LMNAKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL8737052 | 0.82 | KDM4E (0.66) | KDM4ELIPERAB9ANPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL23320590 | 0.81 | ALDH1A1 (0.58) | LMNAKDM4ERAB9ANPC1ALDH1A1 | |
| Potassium SCHEMBL29692209 | 0.81 | KDM4E (0.58) | LMNAKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL23320591 | 0.81 | KDM4E (0.58) | LMNAKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL4597506 | 0.80 | KDM4E (0.54) | KDM4ELIPERAB9ANPC1ALDH1A1 | |
| SCHEMBL4597217 | 0.79 | ACACB (0.44) | LMNAKDM4ELIPEACACB | |
| SCHEMBL8737929 | 0.79 | LMNA (0.87) | LMNAKDM4ERAB9AALDH1A1HSD17B10 | |
| SCHEMBL4598049 | 0.78 | KDM4E (0.56) | LMNAKDM4ELIPERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| US-20070066624-A1 | Chemokine receptor binding compounds | ANORMED, INC. (CA) | 2007-03-22 | — | — | US | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | CCR5, CCR4, CCR1 | LMNA 4700/4885KDM4E 3689/4885LIPE 3734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.