Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F12 | P00748 | 13/20 | 0.58 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.54 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | KRAS | P01116 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29666765 | 0.84 | HDAC4 (0.58) | F12KLKB1HDAC4KRASPLAU | |
| SCHEMBL30787065 | 0.82 | HDAC3 (0.56) | F12PCSK9KLKB1HDAC4 | |
| SCHEMBL29666545 | 0.82 | HDAC4 (0.58) | KLKB1HDAC4PLAU | |
| SCHEMBL26935034 | 0.80 | ITGB3 (0.63) | F12PCSK9HDAC4KRAS | |
| SCHEMBL29526928 | 0.79 | SLC6A3 (0.56) | F12PCSK9KLKB1HDAC4 | |
| SCHEMBL29666853 | 0.79 | KLKB1 (0.57) | F12KLKB1HDAC4PLAU | |
| SCHEMBL29666836 | 0.79 | HDAC4 (0.57) | HDAC4KRAS | |
| SCHEMBL29666795 | 0.78 | KRAS (0.56) | PCSK9KLKB1HDAC4KRAS | |
| SCHEMBL29666550 | 0.78 | HDAC4 (0.62) | KLKB1HDAC4KRAS | |
| SCHEMBL26935056 | 0.78 | ITGB3 (0.61) | PCSK9KLKB1HDAC4KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210130415-A1 | CHEMICALLY-MODIFIED ADENO-ASSOCIATED VIRUS | Université de Nantes (FR) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210130415-A1 | CHEMICALLY-MODIFIED ADENO-ASSOCIATED VIRUS | ALDH1A1, ALDH1A2, GAPDH | F12 857/4885PCSK9 3322/4885KLKB1 4188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.