Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | USP14 | P54578 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22901590 | 0.82 | GABRA1 (0.37) | HPGDBACE1 | |
| SCHEMBL4106972 | 0.79 | CYP3A4 (0.49) | CYP3A4TDP1BACE1USP14 | |
| SCHEMBL2596567 | 0.76 | BACE1 (0.31) | BACE1 | |
| SCHEMBL25239245 | 0.73 | GABRA1 (0.30) | — | |
| SCHEMBL30079928 | 0.73 | USP14 (0.35) | BACE1USP14 | |
| SCHEMBL1922496 | 0.72 | NAAA (0.33) | BACE1 | |
| SCHEMBL5000975 | 0.72 | BACE1 (0.30) | BACE1 | |
| SCHEMBL19022334 | 0.72 | ALDH1A1 (0.31) | ALDH1A1CYP3A4HPGDTDP1 | |
| SCHEMBL1742881 | 0.72 | ALDH1A1 (0.37) | ALDH1A1CYP3A4HPGDTDP1 | |
| SCHEMBL2854902 | 0.71 | VDR (0.36) | BACE1USP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11253600-B2 | Bioorthogonal compositions | TAMBO, INC. (US) | 2022-02-22 | — | — | US | disclosed |
| US-20210128733-A1 | BIOORTHOGONAL COMPOSITIONS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210128733-A1 | BIOORTHOGONAL COMPOSITIONS | TIE1, BBOX1, ST14 | ALDH1A1 3320/4885CYP3A4 2260/4885HPGD 1049/4885 |
| US-11253600-B2 | Bioorthogonal compositions | TIE1, BBOX1, ST14 | ALDH1A1 3320/4885CYP3A4 2260/4885HPGD 1049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.