Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11165745 | 0.86 | L3MBTL1 (0.68) | L3MBTL1HTTSMN1; SMN2TSHR | |
| SCHEMBL10666611 | 0.85 | MEN1 (0.57) | L3MBTL1HTTALDH1A1MEN1KMT2A | |
| SCHEMBL11269875 | 0.85 | L3MBTL1 (0.55) | L3MBTL1HTTALDH1A1MEN1KMT2A | |
| SCHEMBL10546592 | 0.85 | L3MBTL1 (0.71) | L3MBTL1HTTALDH1A1MEN1KMT2A | |
| SCHEMBL10662788 | 0.83 | L3MBTL1 (0.62) | L3MBTL1HTTALDH1A1MEN1KMT2A | |
| SCHEMBL11348784 | 0.83 | L3MBTL1 (0.60) | L3MBTL1HTTALDH1A1MEN1KMT2A | |
| SCHEMBL27837608 | 0.83 | MEN1 (0.65) | L3MBTL1HTTALDH1A1MEN1KMT2A | |
| SCHEMBL11083559 | 0.82 | ALDH1A1 (0.52) | L3MBTL1HTTALDH1A1MEN1KMT2A | |
| SCHEMBL10934750 | 0.81 | SMN1; SMN2 (0.61) | L3MBTL1HTTALDH1A1MEN1KMT2A | |
| SCHEMBL11348788 | 0.80 | L3MBTL1 (0.61) | L3MBTL1HTTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4398940-A | PLANT GROWTH REGULATORS | MONSANTO COMPANY (US) | 1983-08-16 | — | — | US | claimed |
| EP-0003075-A1 | N-Amides of 2-benzothiazolinone and their use as plant growth regulants | MONSANTO COMPANY (US) | 1979-07-25 | — | — | EP | claimed |
| US-3993468-A | INCREASING SUCROSE CONTENT | MONSANTO COMPANY (US) | 1976-11-23 | — | — | US | claimed |
| US-20230277501-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | THE JOHNS HOPKINS UNIVERSITY | 2023-09-07 | — | — | US | disclosed |
| US-20230033195-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | THE JOHNS HOPKINS UNIVERSITY | 2023-02-02 | — | — | US | disclosed |
| US-20220265685-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | THE JOHNS HOPKINS UNIVERSITY | 2022-08-25 | — | — | US | disclosed |
| US-11160785-B2 | Methods and compositions for improving cognitive function | AGENEBIO INC. (US) | 2021-11-02 | — | — | US | disclosed |
| US-20210244709-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | THE JOHNS HOPKINS UNIVERSITY | 2021-08-12 | — | — | US | disclosed |
| EP-3827820-A1 | BRIVARACETAM FOR IMPROVING COGNITIVE FUNCTION | The Johns Hopkins University (US) | 2021-06-02 | — | — | EP | disclosed |
| US-10806717-B2 | Methods and compositions for improving cognitive function | THE JOHNS HOPKINS UNIVERSITY (US) | 2020-10-20 | — | — | US | disclosed |
| US-10624875-B2 | Methods and compositions for treating schizophrenia | THE JOHNS HOPKINS UNIVERSITY (US) | 2020-04-21 | — | — | US | disclosed |
| US-4323677-A | LEGUME PLANT GROWTH REGULATOR | MONSANTO COMPANY (US) | 1982-04-06 | — | — | US | disclosed |
| EP-0009331-A1 | Imides derived from 2-oxo-3-benzothiazoline-acetic acid and butyric acid, process for their preparation and their use as herbicides and as plant growth regulants | MONSANTO COMPANY (US) | 1980-04-02 | — | — | EP | disclosed |
| US-4187097-A | N-hydrazides of 2-benzothiazolinone as plant growth regulants | MONSANTO COMPANY (US) | 1980-02-05 | — | — | US | disclosed |
| US-4185990-A | HERBICIDES AND PLANT GROWTH REGULATORS | MONSANTO COMPANY (US) | 1980-01-29 | — | — | US | disclosed |
| EP-0003075-A1 | N-Amides of 2-benzothiazolinone and their use as plant growth regulants | MONSANTO COMPANY (US) | 1979-07-25 | — | — | EP | disclosed |
| EP-0003075-A1 | N-Amides of 2-benzothiazolinone and their use as plant growth regulants | MONSANTO COMPANY (US) | 1979-07-25 | — | — | EP | disclosed |
| EP-0002613-A1 | N-Hydrazides of 2-benzothiazolinone and their use as plant growth regulants | MONSANTO COMPANY (US) | 1979-06-27 | — | — | EP | disclosed |
| US-4149871-A | ESPECIALLY SOYBEANS | MONSANTO COMPANY (US) | 1979-04-17 | — | — | US | disclosed |
| US-4049419-A | SOYBEAN PLANTS | MONSANTO COMPANY (US) | 1977-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10806717-B2 | Methods and compositions for improving cognitive function | GRIN2A, CHRNA2, SYNGR2 | L3MBTL1 4649/4885HTT 1263/4885ALDH1A1 2177/4885 |
| US-20210244709-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | GRIN2A, CHRNA2, SYNGR2 | L3MBTL1 4649/4885HTT 1263/4885ALDH1A1 2177/4885 |
| US-11160785-B2 | Methods and compositions for improving cognitive function | BACE2, BACE1, GRIN2A | L3MBTL1 2648/4885HTT 352/4885ALDH1A1 1226/4885 |
| US-10624875-B2 | Methods and compositions for treating schizophrenia | RAB2A, SYNGR2, GRIN2A | L3MBTL1 4165/4885HTT 1227/4885ALDH1A1 3810/4885 |
| US-20230277501-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | GRIN2A, CHRNA2, SYNGR2 | L3MBTL1 4649/4885HTT 1263/4885ALDH1A1 2177/4885 |
| US-20220265685-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | BACE1, BACE2, ACHE | L3MBTL1 1983/4885HTT 954/4885ALDH1A1 2614/4885 |
| US-20230033195-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | GRIN2D, GRIN2A, SLC18A2 | L3MBTL1 3586/4885HTT 1585/4885ALDH1A1 2755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.