Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX3 | P23760 | 2/20 | 0.31 |
| ▸ | FOXO1 | Q12778 | 2/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20908683 | 0.85 | CCR2 (0.31) | CCR2 | |
| SCHEMBL9925894 | 0.76 | ALDH1A1 (0.42) | CCR2 | |
| SCHEMBL28285515 | 0.68 | CES1 (0.41) | — | |
| Hydrogen Peroxide SCHEMBL27715852 | 0.68 | CES1 (0.41) | — | |
| SCHEMBL81262 | 0.68 | CES1 (0.41) | — | |
| SCHEMBL7116056 | 0.66 | CES2 (0.43) | — | |
| Acetic Acid SCHEMBL28237398 | 0.63 | CES1 (0.48) | — | |
| SCHEMBL23280225 | 0.63 | NISCH (0.32) | CCR2 | |
| SCHEMBL10783782 | 0.62 | CES2 (0.54) | — | |
| Methylene Chloride SCHEMBL8625445 | 0.61 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11370757-B2 | Photocleavable nitroindoline-based crosslinkers | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2022-06-28 | — | — | US | disclosed |
| US-20210130294-A1 | PHOTOCLEAVABLE NITROINDOLINE-BASED CROSSLINKERS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11370757-B2 | Photocleavable nitroindoline-based crosslinkers | OTUD7B, ALAD, NNMT | PAX3 4315/4885FOXO1 4852/4885CCR2 4504/4885 |
| US-20210130294-A1 | PHOTOCLEAVABLE NITROINDOLINE-BASED CROSSLINKERS | OTUD7B, ALAD, NNMT | PAX3 4315/4885FOXO1 4852/4885CCR2 4504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.