Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | TOP1 | P11387 | 2/20 | 0.49 |
| ▸ | TOP2A | P11388 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30480093 | 0.81 | TERT (0.55) | HTR3AKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL6002185 | 0.81 | HTR3A (1.00) | HTR3AKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL7723267 | 0.81 | TERT (0.55) | HTR3AKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL15534827 | 0.81 | HTR3A (0.50) | HTR3AKDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL526167 | 0.81 | ALDH1A1 (0.63) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL1905445 | 0.79 | MAPT (0.48) | HTR3AKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL20784267 | 0.79 | HTR3A (0.69) | HTR3AKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL4649483 | 0.79 | MAPT (0.59) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL1039861 | 0.78 | DRD2 (0.68) | HTR3AMAPTKMT2AMEN1ADRA2C | |
| SCHEMBL29566812 | 0.78 | DRD2 (0.68) | HTR3AMAPTKMT2AMEN1ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961738-A1 | New compounds with antiglutamatergic properties and uses thereof | Faust Pharmaceuticals (FR) | 2008-08-27 | — | — | EP | disclosed |
| EP-1961738-A1 | New compounds with antiglutamatergic properties and uses thereof | Faust Pharmaceuticals (FR) | 2008-08-27 | — | — | EP | disclosed |
| WO-2008098751-A1 | NEW COMPOUNDS WITH ANTIGLUTAMATERGIC PROPERTIES AND USES THEREOF | FAUST PHARMACEUTICALS (FR) | 2008-08-21 | — | — | WO | disclosed |
| WO-2008098751-A1 | NEW COMPOUNDS WITH ANTIGLUTAMATERGIC PROPERTIES AND USES THEREOF | FAUST PHARMACEUTICALS (FR) | 2008-08-21 | — | — | WO | disclosed |