Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 5/20 | 0.36 |
| ▸ | MMP2 | P08253 | 3/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CSK | P41240 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24925613 | 0.85 | PTPN1 (0.35) | ALDH1A1CTSCLMNAMAPTHTT | |
| SCHEMBL23331972 | 0.83 | PTPN1 (0.34) | ALDH1A1CTSCLMNAMAPTHTT | |
| SCHEMBL24942238 | 0.83 | MMP1 (0.36) | MMP1MMP2MMP3MMP9REN | |
| SCHEMBL24942214 | 0.81 | PTPN1 (0.33) | ALDH1A1CTSCLMNAMAPTHTT | |
| SCHEMBL23332129 | 0.81 | MGLL (0.42) | HSD17B10 | |
| SCHEMBL23306559 | 0.81 | MGLL (0.42) | HSD17B10 | |
| SCHEMBL23306460 | 0.79 | LTA4H (0.47) | ALDH1A1SLC7A5 | |
| SCHEMBL23332010 | 0.79 | LTA4H (0.47) | ALDH1A1SLC7A5 | |
| SCHEMBL23306657 | 0.78 | MMP1 (0.39) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL23306654 | 0.78 | MMP1 (0.39) | ALDH1A1MMP1MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021087083-A1 | USE OF ITACONATE AND ITS DERIVATIVES/ANALOGUES TO INDUCE HAIR GROWTH | THE JOHNS HOPKINS UNIVERSITY (US) | 2021-05-06 | — | — | WO | disclosed |