Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CSK | P41240 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23331972 | 0.91 | PTPN1 (0.34) | PTPN1ALDH1A1LMNAMAPTHTT | |
| SCHEMBL24942214 | 0.89 | PTPN1 (0.33) | PTPN1ALDH1A1LMNAMAPTHTT | |
| SCHEMBL24942238 | 0.88 | MMP1 (0.36) | PTPN1CSKSLC7A5HDAC8 | |
| SCHEMBL23339153 | 0.85 | ALDH1A1 (0.37) | ALDH1A1LMNAMAPTHTTKMT2A | |
| SCHEMBL23332014 | 0.82 | CTSC (0.35) | PTPN1ALDH1A1LMNAMAPTHTT | |
| SCHEMBL24942202 | 0.81 | CTSC (0.34) | PTPN1ALDH1A1LMNAMAPTHTT | |
| SCHEMBL23332129 | 0.80 | MGLL (0.42) | HSD17B10 | |
| SCHEMBL23306559 | 0.80 | MGLL (0.42) | HSD17B10 | |
| SCHEMBL23306460 | 0.78 | LTA4H (0.47) | ALDH1A1SLC7A5LTA4HLNPEP | |
| SCHEMBL23332010 | 0.78 | LTA4H (0.47) | ALDH1A1SLC7A5LTA4HLNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230025922-A1 | USE OF ITACONATE AND ITS DERIVATIVES/ANALOGUES TO INDUCE HAIR GROWTH | THE JOHNS HOPKINS UNIVERSTY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230025922-A1 | USE OF ITACONATE AND ITS DERIVATIVES/ANALOGUES TO INDUCE HAIR GROWTH | LRBA, HADHA, IMPDH1 | PTPN1 2934/4885ALDH1A1 230/4885LMNA 4130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.