Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 7/20 | 0.34 |
| ▸ | CDK9 | P50750 | 7/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20830015 | 0.85 | ALDH1A1 (0.49) | HPGDHCAR3HCAR2ALDH1A1CYP1A2 | |
| SCHEMBL24422182 | 0.80 | HCAR3 (0.38) | HCAR3ALDH1A1SMN1; SMN2DYRK1APDE2A | |
| SCHEMBL1083846 | 0.75 | ALDH1A1 (0.58) | HPGDHCAR3HCAR2ALDH1A1CYP1A2 | |
| SCHEMBL10328043 | 0.75 | SLC9A1 (0.55) | HPGDHCAR3ALDH1A1DYRK1ANFATC1 | |
| SCHEMBL7017031 | 0.71 | POLB (0.55) | ALDH1A1CYP1A2PDE2AKDM4ESLC9A1 | |
| SCHEMBL19191102 | 0.71 | ALDH1A1 (0.41) | ALDH1A1CYP1A2DYRK1ANFATC1GSK3B | |
| SCHEMBL7485062 | 0.71 | ALDH1A1 (0.55) | ALDH1A1CYP1A2PDE2AKDM4ECDK2 | |
| SCHEMBL23523969 | 0.70 | HPGD (0.41) | HPGDHCAR3HCAR2ALDH1A1CYP1A2 | |
| SCHEMBL9911126 | 0.70 | SLC9A1 (0.59) | HCAR3ALDH1A1DYRK1ACLK1KDM4E | |
| SCHEMBL10295524 | 0.70 | HCAR3 (0.44) | HCAR3ALDH1A1CYP1A2DYRK1ANFATC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11661437-B2 | Steroid derivative regulators, method for preparing the same, and uses thereof | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-05-30 | — | — | US | disclosed |
| US-20210139530-A1 | STEROID DERIVATIVE REGULATORS, METHOD FOR PREPARING THE SAME, AND USES THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11661437-B2 | Steroid derivative regulators, method for preparing the same, and uses thereof | GABRR1, GABRB1, GABRD | HPGD 516/4885HCAR3 1396/4885HCAR2 805/4885 |
| US-20210139530-A1 | STEROID DERIVATIVE REGULATORS, METHOD FOR PREPARING THE SAME, AND USES THEREOF | GABRD, GABRR1, GABRA1 | HPGD 553/4885HCAR3 1160/4885HCAR2 701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.