Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11468030 | 0.78 | LMNA (0.40) | LMNASMN1; SMN2GAAMAPTALDH1A1 | |
| SCHEMBL20407535 | 0.73 | SMN1; SMN2 (0.56) | LMNASMN1; SMN2GAAMAPTALDH1A1 | |
| SCHEMBL10721796 | 0.72 | DRD4 (0.65) | LMNASMN1; SMN2GAAMAPTALDH1A1 | |
| SCHEMBL11726248 | 0.72 | LMNA (0.48) | LMNASMN1; SMN2GAAMAPTALDH1A1 | |
| SCHEMBL5488104 | 0.71 | KDM4E (0.57) | LMNASMN1; SMN2GAAALDH1A1MAPK1 | |
| SCHEMBL861408 | 0.69 | SMN1; SMN2 (0.59) | LMNASMN1; SMN2GAAMAPTALDH1A1 | |
| SCHEMBL21985476 | 0.69 | SMN1; SMN2 (0.59) | LMNASMN1; SMN2GAAMAPTALDH1A1 | |
| SCHEMBL13655375 | 0.68 | LMNA (0.84) | LMNASMN1; SMN2GAAMAPTALDH1A1 | |
| SCHEMBL8254760 | 0.68 | DRD2 (0.64) | LMNASMN1; SMN2GAAMAPTALDH1A1 | |
| SCHEMBL11575546 | 0.67 | ALDH1A1 (0.33) | LMNASMN1; SMN2GAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3819328-A1 | THERMALLY-CONDUCTIVE CURABLE COMPOSITION | 3M Innovative Properties Company (US) | 2021-05-12 | — | — | EP | disclosed |